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Gene Expression Data
Assay Details
Assay
Reference: J:143548 Himes AD, et al., Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6471713
Gene symbol: Pcsk2
Gene name: proprotein convertase subtilisin/kexin type 2
Antibody: anti-PC2
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2M: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: adenohypophysis pars intermedia Present Widespread 2M Expression in melanotrophes throughout intermediate lobe.
Specimen 2N: embryonic day 16.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Structure Level Pattern Image Note
TS24: adenohypophysis pars intermedia Ambiguous 2N Very few, if any, cells in the intermediate lobe differentiate into melanotropes
Specimen 2O: embryonic day 16.5; Prop1df/Prop1df (more )
Structure Level Pattern Image Note
TS24: adenohypophysis pars intermedia Present Single cells 2O Occasional expressing cell.
Specimen 2P: embryonic day 16.5; Hes1tm1Fgu/Hes1tm1Fgu, Prop1df/Prop1df (more )
Structure Level Pattern Image Note
TS24: pituitary gland Absent 2P Entire mutant pituitary gland is devoid of expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory