Cited1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:116191 Gerstner JR, et al., Expression of the transcriptional coactivator CITED1 in the adult and developing murine brain. Dev Neurosci. 2007;29(3):203-12
Assay type:	RNA in situ
MGI Accession ID:	MGI:6470795
Gene symbol:	Cited1
Gene name:	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

Probe:	Cited1 probe4
Probe preparation:	Antisense labelled with S35 RNA
Visualized with:	Autoradiography

Results

Specimen 1B/C: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: medial preoptic area	Weak		1B/C

Specimen 1B inset: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: medial preoptic area	Weak	Regionally restricted	1B inset	Low levels of expression in a subset of cells in the medial preoptic area (MPA).

Specimen 1D: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: subfornical organ	Moderate		1D

Specimen 1F/G: postnatal adult (more

)

Structure	Level	Image
TS28: arcuate nucleus	Strong	1F/G
TS28: ventromedial hypothalamic nucleus	Strong	1F/G
TS28: dorsomedial hypothalamic nucleus	Weak	1F/G

Specimen 1F inset: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: hypothalamus	Present	Punctate	1F inset	Punctate pattern of expression consistent with expression in neurons.

Specimen 1H/I: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: lateral dorsal thalamic nucleus	Strong		1H/I
TS28: cerebral cortex	Weak		1H/I

Specimen 1H inset: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: lateral dorsal thalamic nucleus	Present	Diffuse	1H inset	Diffuse expression over some cells in dorsolateral (DL) thalamic nucleus.

Specimen 1J/K: postnatal adult (more

)

Structure	Level	Image
TS28: cerebral cortex	Weak	1J/K
TS28: cortical layer IV	Present	1J/K
TS28: cortical layer VI	Present	1J/K

Specimen 1J inset: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: neocortex	Present	Regionally restricted	1J inset	Expression around large pale, Nissl-staining nuclei, suggestive of expression in neurons.

Specimen 1M/N: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: dorsal raphe nucleus	Strong	Punctate	1M/N

Specimen 1M inset: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: dorsal raphe nucleus	Present	Regionally restricted	1M inset	Expression in dorsal raphe (DR) nucleus in pattern consisted with expression in neurons.

Specimen 3A: embryonic day 16.0 (more

)

Structure	Level	Pattern	Image	Note
TS24: arcuate nucleus	Present		3A

Specimen 3B: embryonic day 18.0 (more

)

Structure	Level	Pattern	Image	Note
TS26: arcuate nucleus	Strong		3B

Specimen 3C: postnatal day 1 (more

)

Structure	Level	Pattern	Image	Note
TS27: arcuate nucleus	Strong		3C

Specimen 3D: postnatal day 5 (more

)

Structure	Level	Pattern	Image	Note
TS28: arcuate nucleus	Strong		3D

Specimen 3E: postnatal day 14 (more

)

Structure	Level	Pattern	Image	Note
TS28: arcuate nucleus	Strong		3E

Specimen 4A: postnatal day 1 (more

)

Structure	Level	Pattern	Image	Note
TS27: cerebellum external granule cell layer	Moderate		4A inset , 4A	Moderate expression in external granule layer (EGL) of cerebellar anlage beginning at birth.

Specimen 4B: postnatal day 5 (more

)

Structure	Level	Image
TS27: cerebellum external granule cell layer	Moderate	4B inset , 4B
TS27: cerebellum Purkinje cell layer	Weak	4B inset , 4B
TS27: cerebellum granule cell layer	Weak	4B inset , 4B
TS27: cerebellum molecular layer	Weak	4B inset , 4B

Specimen 4C: postnatal day 10 (more

)

Structure	Level	Image
TS28: cerebellum external granule cell layer	Present	4C inset , 4C
TS28: cerebellum Purkinje cell layer	Moderate	4C , 4C inset
TS28: cerebellum granule cell layer	Moderate	4C , 4C inset

Specimen 4D: postnatal day 14 (more

)

Structure	Level	Image
TS28: cerebellum external granule cell layer	Weak	4D , 4D inset
TS28: cerebellum Purkinje cell layer	Moderate	4D , 4D inset
TS28: cerebellum granule cell layer	Moderate	4D , 4D inset

Specimen 4E: postnatal day 25 (more

)

Structure	Level	Pattern	Image	Note
TS28: cerebellum Purkinje cell layer	Weak	Single cells	4E inset , 4E	Low levels of expression confined to a few cells in Purkinje cell/granule cell layer (PCL/GCL).
TS28: cerebellum granule cell layer	Weak	Single cells	4E inset , 4E	Low levels of expression confined to a few cells in Purkinje cell/granule cell layer (PCL/GCL).

Specimen Table 1 E16: embryonic day 16.0 (more

)

Structure	Level	Pattern	Note
TS24: arcuate nucleus	Moderate
TS24: retrochiasmatic area	Moderate
TS24: midbrain	Trace	Regionally restricted	Very low expression in parvicellular reticular nucleus.
TS24: dorsomedial hypothalamic nucleus	Absent
TS24: hippocampus	Absent
TS24: main olfactory bulb mitral cell layer	Absent
TS24: medial preoptic nucleus	Absent
TS24: neocortex	Absent
TS24: thalamus	Absent

Specimen Table 1 E18: embryonic day 18.0 (more

)

Structure	Level	Pattern	Note
TS26: arcuate nucleus	Moderate
TS26: retrochiasmatic area	Moderate
TS26: dorsomedial hypothalamic nucleus	Weak
TS26: midbrain	Trace	Regionally restricted	Very low expression in parvicellular reticular nucleus
TS26: dentate gyrus	Absent
TS26: hippocampus CA1	Absent
TS26: hippocampus CA2	Absent
TS26: hippocampus CA3	Absent
TS26: main olfactory bulb mitral cell layer	Absent
TS26: medial preoptic nucleus	Absent
TS26: thalamus	Absent

Specimen Table 1 P1: postnatal day 1 (more

)

Structure	Level	Pattern	Note
TS27: anterior hypothalamic nucleus	Strong
TS27: arcuate nucleus	Strong
TS27: dorsal raphe nucleus	Strong
TS27: retrochiasmatic area	Strong
TS27: dorsomedial hypothalamic nucleus	Moderate
TS27: cerebellum external granule cell layer	Weak
TS27: gigantocellular reticular nucleus	Weak
TS27: median raphe nucleus	Weak
TS27: paramedian raphe nucleus	Weak
TS27: parvicellular reticular nucleus	Weak
TS27: locus coeruleus	Trace
TS27: medial preoptic nucleus	Trace
TS27: superior colliculus	Trace
TS27: caudate-putamen	Trace	Single cells	Sparsely labeled cells.
TS27: corpus striatum	Trace	Single cells	Sparsely labeled cells.
TS27: globus pallidus	Trace	Single cells	Sparsely labeled cells.
TS27: septal nucleus	Trace	Single cells	Sparsely labeled cells.
TS27: cerebellum Purkinje cell layer	Absent
TS27: cerebellum internal granule cell layer	Absent
TS27: cortical layer IV	Absent
TS27: cortical layer VI	Absent
TS27: dentate gyrus	Absent
TS27: hippocampus CA1	Absent
TS27: hippocampus CA2	Absent
TS27: hippocampus CA3	Absent
TS27: main olfactory bulb mitral cell layer	Absent
TS27: thalamus	Absent

Specimen Table 1 P5: postnatal day 5 (more

)

Structure	Level	Pattern	Note
TS28: arcuate nucleus	Very strong
TS28: dorsal raphe nucleus	Strong
TS28: paramedian raphe nucleus	Strong
TS28: retrochiasmatic area	Strong
TS28: anterior hypothalamic nucleus	Moderate
TS28: dorsomedial hypothalamic nucleus	Moderate
TS28: median raphe nucleus	Moderate
TS28: gigantocellular reticular nucleus	Weak
TS28: parvicellular reticular nucleus	Weak
TS28: locus coeruleus	Trace
TS28: medial preoptic nucleus	Trace
TS28: subfornical organ	Trace
TS28: superior colliculus	Trace
TS28: caudate-putamen	Trace	Single cells	Sparcely labeled cells.
TS28: cerebellum external granule cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: cerebellum internal granule cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: corpus striatum	Trace	Single cells	Sparcely labeled cells.
TS28: globus pallidus	Trace	Single cells	Sparcely labeled cells.
TS28: main olfactory bulb mitral cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: septal nucleus	Trace	Single cells	Sparcely labeled cells.
TS28: cerebellum Purkinje cell layer	Absent
TS28: cortical layer IV	Absent
TS28: cortical layer VI	Absent
TS28: dentate gyrus	Absent
TS28: hippocampus CA1	Absent
TS28: hippocampus CA2	Absent
TS28: hippocampus CA3	Absent
TS28: thalamus	Absent

Specimen Table 1 P10: postnatal day 10 (more

)

Structure	Level	Pattern	Note
TS28: arcuate nucleus	Very strong
TS28: dorsal raphe nucleus	Strong
TS28: paramedian raphe nucleus	Strong
TS28: retrochiasmatic area	Strong
TS28: anterior hypothalamic nucleus	Moderate
TS28: dorsomedial hypothalamic nucleus	Moderate
TS28: median raphe nucleus	Moderate
TS28: cerebellum Purkinje cell layer	Weak
TS28: cerebellum external granule cell layer	Weak
TS28: gigantocellular reticular nucleus	Weak
TS28: locus coeruleus	Weak
TS28: medial preoptic nucleus	Weak
TS28: parvicellular reticular nucleus	Weak
TS28: subfornical organ	Weak
TS28: thalamus	Weak
TS28: cerebellum internal granule cell layer	Trace
TS28: cortical layer IV	Trace
TS28: hippocampus CA3	Trace
TS28: superior colliculus	Trace
TS28: caudate-putamen	Trace	Single cells	Sparcely labeled cells.
TS28: corpus striatum	Trace	Single cells	Sparcely labeled cells.
TS28: globus pallidus	Trace	Single cells	Sparcely labeled cells.
TS28: main olfactory bulb mitral cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: septal nucleus	Trace	Single cells	Sparcely labeled cells.
TS28: cortical layer VI	Absent
TS28: dentate gyrus	Absent
TS28: hippocampus CA1	Absent
TS28: hippocampus CA2	Absent

Specimen Table 1 P14: postnatal day 14 (more

)

Structure	Level	Pattern	Note
TS28: arcuate nucleus	Very strong
TS28: dorsal raphe nucleus	Strong
TS28: paramedian raphe nucleus	Strong
TS28: retrochiasmatic area	Strong
TS28: anterior hypothalamic nucleus	Moderate
TS28: dorsomedial hypothalamic nucleus	Moderate
TS28: median raphe nucleus	Moderate
TS28: cerebellum Purkinje cell layer	Weak
TS28: gigantocellular reticular nucleus	Weak
TS28: locus coeruleus	Weak
TS28: medial preoptic nucleus	Weak
TS28: parvicellular reticular nucleus	Weak
TS28: subfornical organ	Weak
TS28: superior colliculus	Weak
TS28: thalamus	Weak
TS28: cortical layer IV	Trace
TS28: cortical layer VI	Trace
TS28: hippocampus CA1	Trace
TS28: hippocampus CA2	Trace
TS28: hippocampus CA3	Trace
TS28: caudate-putamen	Trace	Single cells	Sparcely labeled cells.
TS28: cerebellum external granule cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: cerebellum internal granule cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: corpus striatum	Trace	Single cells	Sparcely labeled cells.
TS28: globus pallidus	Trace	Single cells	Sparcely labeled cells.
TS28: main olfactory bulb mitral cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: septal nucleus	Trace	Single cells	Sparcely labeled cells.
TS28: dentate gyrus	Absent

Specimen Table 1 P25: postnatal day 25 (more

)

Structure	Level	Pattern	Note
TS28: arcuate nucleus	Very strong
TS28: dorsal raphe nucleus	Strong
TS28: paramedian raphe nucleus	Strong
TS28: retrochiasmatic area	Strong
TS28: anterior hypothalamic nucleus	Moderate
TS28: dorsomedial hypothalamic nucleus	Moderate
TS28: median raphe nucleus	Moderate
TS28: cerebellum Purkinje cell layer	Weak
TS28: gigantocellular reticular nucleus	Weak
TS28: medial preoptic nucleus	Weak
TS28: parvicellular reticular nucleus	Weak
TS28: subfornical organ	Weak
TS28: superior colliculus	Weak
TS28: thalamus	Weak
TS28: cortical layer IV	Trace
TS28: cortical layer VI	Trace
TS28: locus coeruleus	Trace
TS28: caudate-putamen	Trace	Single cells	Sparcely labeled cells.
TS28: corpus striatum	Trace	Single cells	Sparcely labeled cells.
TS28: globus pallidus	Trace	Single cells	Sparcely labeled cells.
TS28: main olfactory bulb mitral cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: septal nucleus	Trace	Single cells	Sparcely labeled cells.
TS28: cerebellum internal granule cell layer	Absent
TS28: dentate gyrus	Absent
TS28: hippocampus CA1	Absent
TS28: hippocampus CA2	Absent
TS28: hippocampus CA3	Absent

Specimen Table 1 Adult: postnatal adult (more

)

Structure	Level	Pattern	Note
TS28: arcuate nucleus	Very strong
TS28: dorsal raphe nucleus	Very strong
TS28: median raphe nucleus	Strong
TS28: paramedian raphe nucleus	Strong
TS28: retrochiasmatic area	Strong
TS28: anterior hypothalamic nucleus	Moderate
TS28: dorsomedial hypothalamic nucleus	Moderate
TS28: subfornical organ	Moderate
TS28: gigantocellular reticular nucleus	Weak
TS28: medial preoptic nucleus	Weak
TS28: parvicellular reticular nucleus	Weak
TS28: thalamus	Weak
TS28: cortical layer IV	Trace
TS28: cortical layer VI	Trace
TS28: locus coeruleus	Trace
TS28: superior colliculus	Trace
TS28: caudate-putamen	Trace	Single cells	Sparcely labeled cells.
TS28: cerebellum Purkinje cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: corpus striatum	Trace	Single cells	Sparcely labeled cells.
TS28: globus pallidus	Trace	Single cells	Sparcely labeled cells.
TS28: main olfactory bulb mitral cell layer	Trace	Single cells	Sparcely labeled cells.
TS28: septal nucleus	Trace	Single cells	Sparcely labeled cells.
TS28: cerebellum internal granule cell layer	Absent
TS28: dentate gyrus	Absent
TS28: hippocampus CA1	Absent
TS28: hippocampus CA2	Absent
TS28: hippocampus CA3	Absent

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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