Gene Expression Data
Assay Details
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Assay
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Reference:
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J:262122
Gigante ED, et al., Hypomorphic Smo mutant with inefficient ciliary enrichment disrupts the highest level of vertebrate Hedgehog response. Dev Biol. 2018 May 15;437(2):152-162
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6469351
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Gene symbol:
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Ptch1
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Gene name:
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patched 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
3A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Ptch1tm1Mps/Ptch1+
Smocbb/Smo+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: neural tube |
Present |
Graded |
3A
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Steep ventral-to-dorsal gradient of expression.
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Specimen
3B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Ptch1tm1Mps/Ptch1+
Smocbb/Smocbb
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: neural tube |
Weak |
Regionally restricted |
3B
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Gradient of expression is diminished, indicating reduced expression.
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Analysis Tools
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