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Gene Expression Data
Assay Details
Assay
Reference: J:180304 Tu X, et al., Indian hedgehog requires additional effectors besides Runx2 to induce osteoblast differentiation. Dev Biol. 2012 Feb 1;362(1):76-82
Assay type: RNA in situ
MGI Accession ID: MGI:6468253
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Runx2 probe16
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 3A1: embryonic day 18.5; Gt(ROSA)26Sortm3(Runx2)Flng/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 3A1 Expression in perichondrium and primary spongiosa. Lower level of expression in prehypertrophic and early hypertrophic cartilage.
Specimen 3A2: embryonic day 18.5; Runx2tm1Mjo/Runx2tm1Mjo (more )
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 3A2 Prominent expression in perichondrium and cartilage.
Specimen 3A3: embryonic day 18.5; Gt(ROSA)26Sortm3(Runx2)Flng/Gt(ROSA)26Sor+, Runx2tm1Mjo/Runx2tm1Mjo, Tg(Col2a1-cre)3Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: tibia Present 3A3 No noticeable increase in overall expression.
Specimen 3A4: embryonic day 18.5; Gt(ROSA)26Sortm3(Runx2)Flng/Gt(ROSA)26Sortm3(Runx2)Flng, Runx2tm1Mjo/Runx2tm1Mjo, Tg(Col2a1-cre)3Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: tibia Present 3A4 No noticeable increase in overall expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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