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Gene Expression Data
Assay Details
Assay
Reference: J:292838 Iulianella A, et al., The Hedgehog receptor Patched1 regulates proliferation, neurogenesis, and axon guidance in the embryonic spinal cord. Mech Dev. 2019 Dec;160:103577
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6467295
Gene symbol: Cntn2
Gene name: contactin 2
Results
Specimen 5A: embryonic day 10.5 (more )
Note: Double labeled: red - Tag-1 (Cntn2); green - Shh (assay MGI:6467286); blue - DAPI.
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 5A Expression in commissural axonal tracts.
Specimen 5B: embryonic day 10.5; Ptch1wig/Ptch1wig (more )
Note: Double labeled: red - Tag-1 (Cntn2); green - Shh (assay MGI:6467286); blue - DAPI.
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 5B Authors report aberrant dorsal exit of ventral motor roots. Reduced crossing of commissural fibers in ventral commissure.
Specimen 5C/E: embryonic day 10.5 (more )
Note: Double labeled: red - Tag-1 (Cntn2); green - Shh (assay MGI:6467286); blue - DAPI.
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 5C , 5E Expression in commissural axonal tracts.
Specimen 5D/F: embryonic day 10.5; Ptch1wig/Ptch1wig (more )
Note: Double labeled: red - Tag-1 (Cntn2); green - Shh (assay MGI:6467286); blue - DAPI.
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 5F , 5D Commissural axons fail to target the ventral midline. Aberrant targeting of commissural axons towards floorplate. Dorsal exit of ventral root.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory