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Gene Expression Data
Assay Details
Assay
Reference: J:76173 Vitelli F, et al., Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways. Hum Mol Genet. 2002 Apr 15;11(8):915-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6459262
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Results
Specimen 3G: embryonic day 10.0; Tbx1tm1Bld/Tbx1+ (more )
Structure Level Pattern Image Note
TS16: nervous system Present Regionally restricted 3G Expression in cranial nerves.

Specimen 3H: embryonic day 10.0; Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld (more )
Structure Level Pattern Image Note
TS16: nervous system Present Regionally restricted 3H Authors report anomalies of cranial nerves. Mandibular branch of trigeminal nerve misdirected caudally and fused with branches of facial nerve. Glossopharyngeal nerve is hypoplastic.
TS16: peripheral nervous system Present Regionally restricted 3H Axonal projects show defasciculation and disarray.
TS16: glossopharyngeal-vagus ganglion complex Present 3H Distal ganglia of glossopharyngeal nerve abnormally fused to distal ganglia of vagus nerve.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory