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Gene Expression Data
Assay Details
Assay
Reference: J:76173 Vitelli F, et al., Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways. Hum Mol Genet. 2002 Apr 15;11(8):915-22
Assay type: RNA in situ
MGI Accession ID: MGI:6459261
Gene symbol: Dlx2
Gene name: distal-less homeobox 2
Probe: IMAGE clone 3512916
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3E: embryonic day 10.0; Tbx1tm1Bld/Tbx1+ (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component mesenchyme derived from neural crest Present 3E Expression in postmigratory neural crest cells directed to 1st arch mandibular and maxillary components and to 2nd arch.
TS16: 1st branchial arch maxillary component mesenchyme derived from neural crest Present 3E Expression in postmigratory neural crest cells directed to 1st arch mandibular and maxillary components and to 2nd arch.
TS16: 2nd branchial arch mesenchyme derived from neural crest Present 3E Expression in postmigratory neural crest cells directed to 1st arch mandibular and maxillary components and to 2nd arch.
Specimen 3F: embryonic day 10.0; Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component mesenchyme derived from neural crest Present 3F Expression in neural crest cells in 1st arches.
TS16: 1st branchial arch maxillary component mesenchyme derived from neural crest Present 3F Expression in neural crest cells in 1st arches.
TS16: 2nd branchial arch mesenchyme derived from neural crest Weak 3F Considerably reduced expression in neural crest cells in 2nd arch.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory