Ptch1 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:182970 Saarikangas J, et al., Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia. J Cell Sci. 2011 Apr 15;124(Pt 8):1245-55
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:6455475
Gene symbol:	Ptch1
Gene name:	patched 1

Reporter:	lacZ
	Direct Detection

Results

Specimen S3A MIM+/+ / Ptc+/- (upper): embryonic day 9.5; Ptch1^tm1Mps/Ptch1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		S3A MIM+/+ Ptc+/- (upper)

Specimen S3A MIM-/- / Ptc+/- (upper): embryonic day 9.5; Mtss1^tm1Pla/Mtss1^tm1Pla, Ptch1^tm1Mps/Ptch1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		S3A MIM-/- Ptc+/- (upper)

Specimen S3A MIM+/+ / Ptc+/- (lower): embryonic day 9.5; Ptch1^tm1Mps/Ptch1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		S3A MIM+/+ Ptc+/- (lower)

Specimen S3A MIM-/- / Ptc+/- (lower): embryonic day 9.5; Mtss1^tm1Pla/Mtss1^tm1Pla, Ptch1^tm1Mps/Ptch1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		S3A MIM-/- Ptc+/- (lower)

Specimen S3A MIM+/+ / Ptc-/-: embryonic day 9.5; Ptch1^tm1Mps/Ptch1^tm1Mps (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		S3A MIM+/+ Ptc-/-

Specimen S3A MIM-/- / Ptc-/-: embryonic day 9.5; Mtss1^tm1Pla/Mtss1^tm1Pla, Ptch1^tm1Mps/Ptch1^tm1Mps (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		S3A MIM-/- Ptc-/-	Similar levels of expression in Ptch1-/- and Mim-/- Ptch1-/- embryos.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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