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Gene Expression Data
Assay Details
Assay
Reference: J:284772 DiStasio A, et al., Nubp2 is required for cranial neural crest survival in the mouse. Dev Biol. 2020 Feb 15;458(2):189-199
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6450961
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175) (#9661)
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 6G/G': embryonic day 9.5 (more )
Note: Littermate control; exact genotype not specified.
Structure Level Pattern Image Note
TS15: head mesenchyme derived from neural crest Present 6G/G'
Specimen 6H/H': embryonic day 9.5; Nubp2tm1c(EUCOMM)Hmgu/Nubp2tm1c(EUCOMM)Hmgu, H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tg(Wnt1-GAL4)11Rth/0 (more )
Note: Conditional mutant. Conditional knockout; genotype might be flox/-; Cre.
Structure Level Pattern Image Note
TS15: head mesenchyme derived from neural crest Present 6H/H' Increased apoptosis compared with the control.
Specimen 6J/J': embryonic day 10.5 (more )
Note: Littermate control; exact genotype not specified.
Structure Level Pattern Image Note
TS17: head mesenchyme derived from neural crest Present 6J/J'
Specimen 6K/K': embryonic day 10.5; Nubp2tm1c(EUCOMM)Hmgu/Nubp2tm1c(EUCOMM)Hmgu, H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tg(Wnt1-GAL4)11Rth/0 (more )
Note: Conditional mutant. Conditional knockout; genotype might be flox/-; Cre.
Structure Level Pattern Image Note
TS17: head mesenchyme derived from neural crest Present 6K/K' A drastic increase compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/24/2026
MGI 6.24 		The Jackson Laboratory