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Gene Expression Data
Assay Details
Assay
Reference: J:289658 Francisco MA, et al., Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth. J Exp Med. 2020 May 4;217(5)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441955
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6 (#PRB-278P; #30130, #901301)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen H top +/+: postnatal day 7 (more )
Note: Triple labeled: green - Pax6; purple - Mki67 (assay MGI:6441959); the specimen is also stained with pHis3 (red).
Structure Level Pattern Image Note
TS28: cerebellum Present S2H +/+ top Pax6/pHis3 , S2H +/+ top Pax6/Ki67
Specimen H top -/-: postnatal day 7; Clic1em2Tcp/Clic1em2Tcp (more )
Note: Triple labeled: green - Pax6; purple - Mki67 (assay MGI:6441959); the specimen is also stained with pHis3 (red).
Structure Level Pattern Image Note
TS28: cerebellum Present S2H -/- top Pax6/Ki67 , S2H -/- top Pax6/pHis3 The cerebellum architecture in the mutant is comparable to wild type.
Specimen H bottom +/+: postnatal day 7 (more )
Note: Triple labeled: green - Pax6; purple - Mki67 (assay MGI:6441959); the specimen is also stained with pHis3 (red).
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present S2H +/+ bottom Pax6 , S2H +/+ bottom Pax6/Ki67 , S2H +/+ bottom Pax6/pHis3
Specimen H bottom -/-: postnatal day 7; Clic1em2Tcp/Clic1em2Tcp (more )
Note: Triple labeled: green - Pax6; purple - Mki67 (assay MGI:6441959); the specimen is also stained with pHis3 (red).
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Present S2H -/- bottom Pax6 , S2H -/- bottom Pax6/pHis3 , S2H -/- bottom Pax6/Ki67 The cerebellum architecture in the mutant is comparable to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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