About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:199297 Kitagawa M, et al., Hes1 and Hes5 regulate vascular remodeling and arterial specification of endothelial cells in brain vascular development. Mech Dev. 2013 Sep-Oct;130(9-10):458-66
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441785
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-PECAM1
Detection system: Alexa Fluor 488
Results
Specimen 4A: embryonic day 10.5; Hes1tm1Kag/Hes1+, Hes5tm1Fgu/Hes5tm1Fgu (more )
Structure Level Pattern Image Note
TS17: brain vascular element Present 4A

Specimen 4B: embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Kag, Hes5tm1Fgu/Hes5tm1Fgu, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: brain vascular element Present Regionally restricted 4B Many small fragmented vessels in neural tube compared with control.

Specimen 5C: embryonic day 10.5; Hes1tm1Kag/Hes1+, Hes5tm1Fgu/Hes5tm1Fgu (more )
Note: Double labeled: green - Pecam1; red - Acta2 (assay MGI:6441788),
Structure Level Pattern Image Note
TS17: internal carotid artery Present 5C

Specimen 5D: embryonic day 10.5; Hes1tm1Fgu/Hes1tm1Kag, Hes5tm1Fgu/Hes5tm1Fgu, Tg(Tek-cre)12Flv/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Acta2 (assay MGI:6441788),
Structure Level Pattern Image Note
TS17: internal carotid artery Present 5D Expression not affected compared with control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/06/2026
MGI 6.24
The Jackson Laboratory