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Gene Expression Data
Assay Details
Assay
Reference: J:229475 Prunskaite-Hyyrylainen R, et al., Wnt4 coordinates directional cell migration and extension of the Mullerian duct essential for ontogenesis of the female reproductive tract. Hum Mol Genet. 2016 Mar 15;25(6):1059-73
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441526
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: anti-alphaSMA (ab5694)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6G: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: myometrium inner circular smooth muscle layer Present 6G
TS28: myometrium outer longitudinal smooth muscle layer Present 6G
Specimen 6H: postnatal day 21; Wnt4tm3Svo/Wnt4tm3Svo (more )
Structure Level Pattern Image Note
TS28: myometrium Present 6H Thinner myometrium layer compared with the wild-type.
Specimen 6I: postnatal day 21; Wnt4tm3Svo/Wnt4tm3Svo (more )
Structure Level Pattern Image Note
TS28: genitourinary system Present Regionally restricted 6I Expressed in the smooth muscle cells in the vas deferens-like structure.
Specimen 7C: postnatal month 5 (more )
Structure Level Pattern Image Note
TS28: myometrium inner circular smooth muscle layer Present 7C
TS28: myometrium outer longitudinal smooth muscle layer Present 7C
TS28: vasculature of uterus Present 7C Expressed in the smooth muscle cells in the blood vessels in the endometrium.
Specimen 7D: postnatal month 5; Wnt4tm3Svo/Wnt4tm3Svo (more )
Structure Level Pattern Image Note
TS28: myometrium Present 7D Failed to form two layers.
TS28: vasculature of uterus Present Regionally restricted 7D Expressed in the smooth muscle cells in the blood vessels in the endometrium. The number of blood vessels was reduced.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory