Wnt4^tm3Svo
Targeted Allele Detail

Summary

• Symbol: Wnt4^tm3Svo
• Name: wingless-type MMTV integration site family, member 4; targeted mutation 3, Seppo Vainio
• MGI ID: MGI:6342948
• Synonyms: Wnt4^mCh
• Gene: Wnt4 Location: Chr4:137004946-137026812 bp, + strand Genetic Position: Chr4, 69.8 cM
• Alliance: Wnt4^tm3Svo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229475
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Hypomorph, Reporter)
• Mutation: Insertion
• A monomeric Cherry (mCherry) reporter gene was inserted into exon 1. (J:229475)

Expression

In Mice Carrying this Mutation:

13 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wnt4 Mutation: 21 strains or lines available

References

• Original: J:229475 Prunskaite-Hyyrylainen R, et al., Wnt4 coordinates directional cell migration and extension of the Mullerian duct essential for ontogenesis of the female reproductive tract. Hum Mol Genet. 2016 Mar 15;25(6):1059-73
• All: 2 reference(s)