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Gene Expression Data
Assay Details
Assay
Reference: J:287370 Chen W, et al., Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy. Elife. 2020 Feb 19;9:e48705
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6437218
Gene symbol: Rbfox3
Gene name: RNA binding protein, fox-1 homolog (C. elegans) 3
Antibody: anti-NeuN (ABN90)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 7A/B +/+: postnatal month 2-4 (more )
Note: Triple labeled: blue - Rbfox3; green - Pvalb (assay MGI:6437220); magenta - Sst (assay MGI:6437221)
Structure Level Pattern Image Note
TS28: somatosensory cortex Present 7B Merge upper , 7B NeuN upper , 7A upper
Specimen 7A/B +/-: postnatal month 2-4; Stxbp1tm1d(EUCOMM)Hmgu/Stxbp1+ (more )
Note: Triple labeled: blue - Rbfox3; green - Pvalb (assay MGI:6437220); magenta - Sst (assay MGI:6437221)
Structure Level Pattern Image Note
TS28: somatosensory cortex Present 7B NeuN lower , 7A lower , 7B Merge lower There is the same neuronal density in the hets as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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