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Gene Expression Data
Assay Details
Assay
Reference: J:287370 Chen W, et al., Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy. Elife. 2020 Feb 19;9:e48705
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6437221
Gene symbol: Sst
Gene name: somatostatin
Antibody: anti-Sst (T-4103)
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen 7A/B +/+: postnatal month 2-4 (more )
Note: Triple labeled: magenta - Sst; blue - Rbfox3 (assay MGI:6437218); green - Pvalb (assay MGI:6437220)
Structure Level Pattern Image Note
TS28: somatosensory cortex Present 7A upper , 7B Merge upper , 7B Sst upper
Specimen 7A/B +/-: postnatal month 2-4; Stxbp1tm1d(EUCOMM)Hmgu/Stxbp1+ (more )
Note: Triple labeled: magenta - Sst; blue - Rbfox3 (assay MGI:6437218); green - Pvalb (assay MGI:6437220)
Structure Level Pattern Image Note
TS28: somatosensory cortex Present Single cells 7A lower , 7B Sst lower , 7B Merge lower There is the same number of somatostatin-expressing interneurons in hets as in wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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