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Gene Expression Data
Assay Details
Assay
Reference: J:134489 Trowe MO, et al., Deafness in mice lacking the T-box transcription factor Tbx18 in otic fibrocytes. Development. 2008 May;135(9):1725-34
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6436334
Gene symbol: Tbx18
Gene name: T-box18
Reporter: lacZ
Direct Detection
Results
Specimen 8I: embryonic day 12.5; Tbx18tm1.1Akis/Tbx18+ (more )
Structure Level Pattern Image Note
TS20: inner ear mesenchyme Present Regionally restricted 8I Expression was restricted to the inner ring of the otic mesenchyme.
Specimen 8J: embryonic day 13.5; Tbx18tm1.1Akis/Tbx18+ (more )
Structure Level Pattern Image Note
TS21: inner ear mesenchyme Present Regionally restricted 8J Expression was restricted to the inner ring of the otic mesenchyme.
Specimen 8K: embryonic day 14.5; Tbx18tm1.1Akis/Tbx18+ (more )
Structure Level Pattern Image Note
TS22: inner ear mesenchyme Present Regionally restricted 8K Expression was restricted to the inner ring of the otic mesenchyme.
Specimen 8L: embryonic day 12.5; Tbx18tm1.1Akis/Tbx18tm2Akis (more )
Structure Level Pattern Image Note
TS20: inner ear mesenchyme Present Regionally restricted 8L Expression was restricted to the inner ring of the otic mesenchyme.
Specimen 8M: embryonic day 13.5; Tbx18tm1.1Akis/Tbx18tm2Akis (more )
Structure Level Pattern Image Note
TS21: inner ear mesenchyme Present Regionally restricted 8M The beta-galactosidase positive area expanded into the outer ring of condensing mesenchymal cells at E13.5.
Specimen 8N: embryonic day 14.5; Tbx18tm1.1Akis/Tbx18tm2Akis (more )
Structure Level Pattern Image Note
TS22: inner ear mesenchyme Present 8N
TS22: otic capsule Present Regionally restricted 8N The expanding expression of the mutant reached the outer lining of the cartilaginous otic capsule at E14.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory