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Targeted Allele Detail
Symbol: Tbx18tm1.1Akis
Name: T-box18; targeted mutation 1.1, Andreas Kispert
MGI ID: MGI:3044915
Synonyms: Tbx18 delta neo, Tbx18LacZ
Gene: Tbx18  Location: Chr9:87584853-87613313 bp, - strand  Genetic Position: Chr9, 47.06 cM, cytoband E3.2
Alliance: Tbx18tm1.1Akis page
Germline Transmission:  Earliest citation of germline transmission: J:90513
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1/SvImJ
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe floxed neo cassette was removed via cre mediated recombination of Tbx18tm1Akis. The phenotype of this allele is the same as for Tbx18tm1Akis. LacZ expression does not recapitulate endogenous expression. (J:90513)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 22 assay results
In Structures Affected by this Mutation: 12 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx18 Mutation:  36 strains or lines available
Original:  J:90513 Bussen M, et al., The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev. 2004 May 15;18(10):1209-21
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.23
The Jackson Laboratory