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Gene Expression Data
Assay Details
Assay
Reference: J:138379 Gu S, et al., Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42
Assay type: RNA in situ
MGI Accession ID: MGI:6434477
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Probe: Col X probe1
Probe preparation: labelled with digoxigenin RNA
Results
Specimen E14.5 wildtype not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mandible condylar condensation Absent
Specimen E14.5 mutant not shown: embryonic day 14.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: mandible condylar condensation Absent
Specimen 8E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: mandible condylar process Strong Regionally restricted 8E Strong expression with restricted localization in hypertrophic chondrocytes of condyle.
TS23: Meckel's cartilage Absent 8E
Specimen 8F: embryonic day 15.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: mandible condylar process Absent 8F
TS23: Meckel's cartilage Absent 8F
Specimen 8G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mandible condylar process Strong Regionally restricted 8G Strong expression with restricted localization in hypertrophic chondrocytes of condyle.
TS24: Meckel's cartilage Absent 8G
Specimen 8H: embryonic day 16.5; Shox2tm1Ddu/Shox2tm1Ypc, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: mandible condylar process Weak 8H Expresssion detectable in mutant at E16.5.
TS24: Meckel's cartilage Absent 8H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory