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Gene Expression Data
Assay Details
Assay
Reference: J:74070 Lauder JM, et al., Expression of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors in the mouse embryo. Int J Dev Neurosci. 2000 Nov;18(7):653-62
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6433997
Gene symbol: Htr2b
Gene name: 5-hydroxytryptamine (serotonin) receptor 2B
Antibody: 5-HT-2B-R antibody (C-terminus)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: The authors did not specify which antibody was used. It is possible a N-terminal anitbody was used in the assay: 5-HT-2B-R antibody (N-terminus) (MGI:6432841), or mAb A72-1 (MGI:6432851).
Results
Specimen 3A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: 1st branchial arch mesenchyme Very strong 3A
TS13: future brain neural fold Very strong 3A
TS13: head mesenchyme derived from neural crest Very strong 3A
TS13: future spinal cord Present 3A
Specimen 3B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: head surface ectoderm Present Regionally restricted 3B Expression is in the epithelium adjacent to the forebrain.
TS16: head mesenchyme Present Regionally restricted 3B Expression is in the mesenchyme adjacent to the forebrain.
Specimen 3C: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: head surface ectoderm Present Regionally restricted 3C Expression is in the epithelium adjacent to the forebrain.
TS16: head mesenchyme Present Regionally restricted 3C Expression is in the mesenchyme adjacent to the forebrain.
TS16: cardiac muscle tissue Present 3C
TS16: gut Present 3C
TS16: somite Present 3C
Specimen 3D: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: gut Present 3D
TS16: somite Present 3D
Specimen 3E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: atrioventricular endocardial cushion Present 3E
TS17: cardiac muscle tissue Present 3E
TS17: outflow tract endocardial cushion Present 3E
Specimen 3F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain floor plate Present 3F
Specimen 3G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: atrioventricular endocardial cushion Present 3G
TS19: cardiac muscle tissue Present 3G
TS19: outflow tract endocardial cushion Present 3G
Specimen 3H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: myelencephalon floor plate Present 3H
Specimen 3I: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: fronto-nasal process ectoderm Present 3I
TS19: fronto-nasal process mesenchyme Present 3I
Specimen 4A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nasal septum cartilage Present 4A
Specimen 4B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tooth Present 4B
TS23: tongue muscle Present Regionally restricted 4B Expression is in non-striated muscle cells.
Specimen 4C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: Meckel's cartilage Present 4C
Specimen 4D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: vibrissa follicle Present 4D
Specimen 4E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: Meckel's cartilage Present 4E
Specimen 4F: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: vibrissa follicle Present 4F
Specimen 4G: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: chondrocranium Present 4G
Specimen 4H: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: tooth Present 4H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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