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Gene Expression Data
Assay Details
Assay
Reference: J:235891 Cimino I, et al., Novel role for anti-Mullerian hormone in the regulation of GnRH neuron excitability and hormone secretion. Nat Commun. 2016 Jan 12;7:10055
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6432767
Gene symbol: Gnrh1
Gene name: gonadotropin releasing hormone 1
Antibody: Anti-GnRH
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Two antibodies were described, but the one used in this assay was not specified. Either MGI:6432388 or MGI:6432389 was used.
Results
Specimen 1e: postnatal day 120 (more )
Note: Double labeled: green - Gnrh1; red - Amhr2 (assay MGI:6432395).
Structure Level Pattern Image Note
TS28: hypothalamus Present 1e
Specimen 1f: postnatal day 120 (more )
Note: Double labeled: green - Gnrh1; red - Amhr2 (assay MGI:6432395).
Structure Level Pattern Image Note
TS28: hypothalamus Present 1f
Specimen 2a: embryonic day 12.5 (more )
Note: Double labeled: green - Gnrh1; red - Amhr2 (assay MGI:6432395).
Structure Level Pattern Image Note
TS20: nose Present Regionally restricted 2a , 2c Expression was detected in neurons migrating out of the vomeronasal organ. The neurons were also immunopositive for Amhr2.
Specimen 2d: postnatal day 90-120 (more )
Note: Double labeled: green - Gnrh1; red - Amhr2 (assay MGI:6432395).
Structure Level Pattern Image Note
TS28: hypothalamus Present Regionally restricted 2d , 2f , 2g , 2i More than 50% of Gnrh1-positive neurons were also immunopositive for Amhr2.
Specimen S1b: postnatal day 90-120 (more )
Note: Double labeled: green - Gnrh1; red - Amhr2 (assay MGI:6432395).
Structure Level Pattern Image Note
TS28: medial septal nucleus Present S1c , S1b , S1e More than 50% of the Gnrh1-positive neurons were also immunopositive for Amhr2.
Specimen S1f: postnatal day 90-120 (more )
Note: Double labeled: green - Gnrh1; red - Amhr2 (assay MGI:6432395).
Structure Level Pattern Image Note
TS28: basal forebrain Present Regionally restricted S1f , S1h More than 50% of the Gnrh1-positive neurons were also immunopositive for Amhr2 in the diagonal band of Broca.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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