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Gene Expression Data
Assay Details
Assay
Reference: J:286046 Xu T, et al., Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development. J Cell Biochem. 2018 Jul;119(7):5852-5863
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6431066
Gene symbol: Smad1
Gene name: SMAD family member 1
Antibody: anti-phospho-Smad1/5 (Ser463/Ser465; 41D10; 9516)
Detection system: Secondary antibody
Assay notes: The antibody used in this assay recognizes the phosphorylated form of the protein.
Results
Specimen 5C WT: embryonic day 18.5; Dnmt3btm5.1Enl/Dnmt3btm5.1Enl (more )
Structure Level Pattern Image Note
TS26: tibia Present Single cells 5C3 , 5C7 , 5C5 Expression is present in hypertrophic chondrocytes.
Specimen 5C mutant: embryonic day 18.5; Dnmt3btm5.1Enl/Dnmt3btm5.1Enl, Tg(Col2a1-cre)1Bhr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: tibia Present Single cells 5C4 , 5C6 , 5C8 Expression is present in hypertrophic chondrocytes. Expression is significantly decreased in the mutant compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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