Gene Expression Data
Assay Details
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Assay
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Reference:
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J:286046
Xu T, et al., Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development. J Cell Biochem. 2018 Jul;119(7):5852-5863
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6431062
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Gene symbol:
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Pcna
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Gene name:
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proliferating cell nuclear antigen
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Results
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Specimen
4A WT:
(close  )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6 * SJL
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Mutant Allele(s):
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Dnmt3btm5.1Enl/Dnmt3btm5.1Enl
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tibia |
Present |
Single cells |
4A5
,
4A3
,
4A1
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Chondrocyte proliferation was observed in the reserve zone (red box) and proliferating columnar zone (yellow box).
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Specimen
4A mutant:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6 * SJL
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Mutant Allele(s):
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Dnmt3btm5.1Enl/Dnmt3btm5.1Enl
Tg(Col2a1-cre)1Bhr/0
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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10% Formalin
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: tibia |
Present |
Single cells |
4A2
,
4A6
,
4A4
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Chondrocyte proliferation was observed in the reserve zone (red box) and proliferating columnar zone (yellow box). No difference was observed between mutants and controls.
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Analysis Tools
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