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Gene Expression Data
Assay Details
Assay
Reference: J:165724 Yu S, et al., Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development. Dev Biol. 2010 Nov 1;347(1):92-108
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6423682
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Results
Specimen S1B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present S1B
Specimen S1B': embryonic day 13.5; Fgf8tm1Mrc/Fgf8tm2Moon, Isl1tm1(cre)Sev/Isl1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: lung epithelium Present S1B' Authors report normal expression.
Specimen S2C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present S2C
Specimen S2C': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present S2C'
Specimen S2D: embryonic day 14.5; Fgf8tm1Mrc/Fgf8tm2Moon, Isl1tm1(cre)Sev/Isl1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: lung epithelium Present S2D Authors report normal expression.
Specimen S2D': embryonic day 14.5; Fgf8tm1Mrc/Fgf8tm2Moon, Isl1tm1(cre)Sev/Isl1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: lung epithelium Present S2D' Authors report normal expression.
Specimen S3C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present S3C
Specimen S3C': embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present S3C'
Specimen S3D: embryonic day 14.5; Fgf8tm1Mrc/Fgf8tm3Mrc (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present S3D Authors report normal expression.
Specimen S3D': embryonic day 14.5; Fgf8tm1Mrc/Fgf8tm3Mrc (more )
Structure Level Pattern Image Note
TS22: lung epithelium Present S3D' Authors report normal expression.
Specimen 9G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung epithelium Weak Regionally restricted 9G Expression in few cuboidal cell at airspace interface.
Specimen 9H: embryonic day 18.5; Fgf8tm1Mrc/Fgf8tm2Moon, Isl1tm1(cre)Sev/Isl1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: lung epithelium Present Regionally restricted 9H Expression in many undifferentiated cells lining small airspaces.
Specimen 10C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung epithelium Weak Regionally restricted 10C
Specimen 10C': embryonic day 18.5; Fgf8tm1Mrc/Fgf8tm3Mrc (more )
Structure Level Pattern Image Note
TS26: lung epithelium Present Regionally restricted 10C' Authors report same expression abnormalities at as in Fgf8/Isl1Cre mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory