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Gene Expression Data
Assay Details
Assay
Reference: J:149463 Lania G, et al., Early thyroid development requires a Tbx1-Fgf8 pathway. Dev Biol. 2009 Apr 1;328(1):109-17
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6423607
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Antibody: anti-FGF8
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 4a: embryonic day 9.0; Mesp1tm2(cre)Ysa/Mesp1+, Tbx1tm1Bld/Tbx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: thyroid primordium mesenchyme Present Regionally restricted 4a
Specimen 4a': embryonic day 9.0; Mesp1tm2(cre)Ysa/Mesp1+, Tbx1tm1Bld/Tbx1tm3Bld (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: thyroid primordium mesenchyme Weak Regionally restricted 4a' Expression downregulated in mutant.
Specimen 4b: embryonic day 9.0; Mesp1tm2(cre)Ysa/Mesp1+, Tbx1tm1Bld/Tbx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: thyroid primordium mesenchyme Present Regionally restricted 4b Expression in mesoderm caudal to thyroid primordium.
Specimen 4b': embryonic day 9.0; Mesp1tm2(cre)Ysa/Mesp1+, Tbx1tm1Bld/Tbx1tm3Bld (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: thyroid primordium mesenchyme Weak Regionally restricted 4b' Expression downregulated in mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory