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Gene Expression Data
Assay Details
Assay
Reference: J:272566 Yang R, et al., CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6423304
Gene symbol: Krt19
Gene name: keratin 19
Antibody: Anti-Cytokeratin 19 [EP1580Y] (ab52625)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 3F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: bile duct Present 3F

Specimen 3F': embryonic day 16.5; Cdk5rap3tm1b(EUCOMM)Hmgu/Cdk5rap3tm1b(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS24: bile duct Absent 3F'

Specimen 5C: postnatal month 1 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS28: bile duct Present 5C

Specimen 5C': postnatal month 1; Cdk5rap3tm1c(EUCOMM)Hmgu/Cdk5rap3tm1c(EUCOMM)Hmgu, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: bile duct Present 5C' All conditional knockout livers contained immunopositive tubular and ductal plate-like structures, but the structural organization varied considerably from liver to liver.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory