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Gene Expression Data
Assay Details
Assay
Reference: J:285611 Russo I, et al., p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits. Cereb Cortex. 2019 Jan 1;29(1):91-105
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6416562
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Antibody: anti-TTF-1 (clone 8G7G3/1)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 5K +/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present 5K left Expressed in the interneuron progenitors.

Specimen 5K -/-: embryonic day 12.5; Srcin1tm1Fdc/Srcin1tm1Fdc (more )
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present 5K right Expressed in the interneuron progenitors.

Specimen S2D MZ +/+: embryonic day 12.5 (more )
Note: Data was quantified in Fig S2E.
Structure Level Pattern Image Note
TS20: telencephalon mantle layer Weak S2D upper left Expressed in the interneuron progenitors in medial ganglionic eminence.

Specimen S2D MZ -/-: embryonic day 12.5; Srcin1tm1Fdc/Srcin1tm1Fdc (more )
Note: Data was quantified in Fig S2E.
Structure Level Pattern Image Note
TS20: telencephalon mantle layer Weak S2D lower left Higher number of positive nuclei in medial ganglionic eminence, compared with the wild-type.

Specimen S2D SVZ +/+: embryonic day 12.5 (more )
Note: Data was quantified in Fig S2E.
Structure Level Pattern Image Note
TS20: telencephalon subventricular zone Present S2D upper middle Expressed in the interneuron progenitors in medial ganglionic eminence.

Specimen S2D SVZ -/-: embryonic day 12.5; Srcin1tm1Fdc/Srcin1tm1Fdc (more )
Note: Data was quantified in Fig S2E.
Structure Level Pattern Image Note
TS20: telencephalon subventricular zone Present S2D lower middle Higher number of positive nuclei in medial ganglionic eminence, compared with the wild-type.

Specimen S2D VZ +/+: embryonic day 12.5 (more )
Note: Data was quantified in Fig S2E.
Structure Level Pattern Image Note
TS20: telencephalon ventricular layer Present S2D upper right Expressed in the interneuron progenitors in medial ganglionic eminence.

Specimen S2D VZ -/-: embryonic day 12.5; Srcin1tm1Fdc/Srcin1tm1Fdc (more )
Note: Data was quantified in Fig S2E.
Structure Level Pattern Image Note
TS20: telencephalon ventricular layer Present S2D lower right Higher number of positive nuclei in medial ganglionic eminence, compared with the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory