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Gene Expression Data
Assay Details
Assay
Reference: J:203431 Collette NM, et al., Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner. Dev Biol. 2013 Nov 1;383(1):90-105
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6406365
Gene symbol: Gli3
Gene name: GLI-Kruppel family member GLI3
Antibody: anti-Gli3
Detection system: Alexa Fluor
Results
Specimen 7A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb ectoderm Present 7A

Specimen 7B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb ectoderm Present 7B Expression in ectoderm and underlying mesenchyme.
TS19: limb mesenchyme Present 7B Expression in ectoderm and underlying mesenchyme.

Specimen 7C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present Regionally restricted 7C Expression in pre-chondrocytes in cartilage condensations.

Specimen 7D: embryonic day 11.5; Sosttm1Paz/Sosttm1Paz, Sostdc1tm1Myan/Sostdc1tm1Myan (more )
Structure Level Pattern Image Note
TS19: limb ectoderm Trace 7D Expression in ectoderm dramatically reduced compared with wild type.

Specimen 7E: embryonic day 11.5; Sosttm1Paz/Sosttm1Paz, Sostdc1tm1Myan/Sostdc1tm1Myan (more )
Structure Level Pattern Image Note
TS19: limb ectoderm Trace 7E Dramatic reduction in expression in both ectoderm and underlying mesenchyme.
TS19: limb mesenchyme Trace 7E Dramatic reduction in expression in both ectoderm and underlying mesenchyme.

Specimen 7F: embryonic day 11.5; Sosttm1Paz/Sosttm1Paz, Sostdc1tm1Myan/Sostdc1tm1Myan (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Ambiguous Regionally restricted 7F Little expression in cartilage anlagen.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory