Gli1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:203431 Collette NM, et al., Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner. Dev Biol. 2013 Nov 1;383(1):90-105
Assay type:	RNA in situ
MGI Accession ID:	MGI:6406360
Gene symbol:	Gli1
Gene name:	GLI-Kruppel family member GLI1

Probe:	Gli1 probe39
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

6E WT ©

Specimen 6E WT: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: limb bud	Present		6E WT

6E Sost-/- ©

Specimen 6E Sost-/-: embryonic day 11.5; Sost^tm1Paz/Sost^tm1Paz (more

)

Structure	Level	Pattern	Image	Note
TS19: limb bud	Present		6E Sost-/-

Specimen 6E Sostdc1-/-: embryonic day 11.5; Gli3^Xt-J/Gli3⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: limb bud	Present		6E Sostdc1-/-

Specimen 6E Sost-/-;Sostdc1-/-: embryonic day 11.5; Sost^tm1Paz/Sost^tm1Paz, Sostdc1^tm1Myan/Sostdc1^tm1Myan (more

)

Structure	Level	Pattern	Image	Note
TS19: limb bud	Strong	Regionally restricted	6E Sost-/-;Sostdc1-/-	Expression dramatically expanded relative to all other genotypes.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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