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Gene Expression Data
Assay Details
Assay
Reference: J:149502 Hill P, et al., A SHH-independent regulation of Gli3 is a significant determinant of anteroposterior patterning of the limb bud. Dev Biol. 2009 Apr 15;328(2):506-16
Assay type: RNA in situ
MGI Accession ID: MGI:6404104
Gene symbol: Hoxd11
Gene name: homeobox D11
Probe: Hoxd11 probe24
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb digit mesenchyme Present Widespread 5G Expression in all digit condensations.
TS20: forelimb mesenchyme Present Regionally restricted 5G Additional proximal expression domain in wrist region.
Specimen 5H: embryonic day 12.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS20: forelimb digit mesenchyme Present Widespread 5H Expression in all digit condensations.
TS20: forelimb mesenchyme Present Regionally restricted 5H Expression in proximal domain markedly weakened, especially in central part.
Specimen 5I: embryonic day 12.5; Gli3tm1Urt/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS20: forelimb digit mesenchyme Present Regionally restricted 5I No expression in anterior digit condensations.
TS20: forelimb mesenchyme Present Regionally restricted 5I Normal level of proximal expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory