Gene Expression Data
Assay Details
Assay
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Reference:
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J:144432
Hajihosseini MK, et al., Evidence that Fgf10 contributes to the skeletal and visceral defects of an apert syndrome mouse model. Dev Dyn. 2009 Feb;238(2):376-85
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6402525
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Gene symbol:
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Fgfr2
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Gene name:
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fibroblast growth factor receptor 2
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Probe:
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Fgfr2-IIIb cDNA5
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
3C:
(close )
Genetic Background:
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involves: 129 * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgf10tm1Wss/Fgf10+ Fgfr2tm2.3Dsn/Fgfr2+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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non-rescued sample
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Structure |
Level |
Pattern |
Image |
Note |
TS25: coronal suture |
Present |
Regionally restricted |
3C
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Expression was stronger and localised to the edges of the bones as well as sutural mesenchymal cells, displaced to the sides of the fusing parietal and frontal bones.
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Specimen
3E:
embryonic day 17.5
(more )
Specimen
3E:
(close )
Genetic Background:
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involves: 129 * 129X1/SvJ * C57BL/6J
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
4B/B':
embryonic day 17.5
(more )
Specimen
4B/B':
(close )
Genetic Background:
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involves: 129 * 129X1/SvJ * C57BL/6J
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
4E/E':
(close )
Genetic Background:
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involves: 129 * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgfr2tm2.3Dsn/Fgfr2+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
4H/H':
(close )
Genetic Background:
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involves: 129 * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgf10tm1Wss/Fgf10+ Fgfr2tm2.3Dsn/Fgfr2+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Specimen
not shown:
embryonic day 17.5; Fgfr2tm2.3Dsn/Fgfr2 +
(more )
Specimen
not shown:
(close )
Genetic Background:
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involves: 129 * 129X1/SvJ * C57BL/6J
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Mutant Allele(s):
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Fgfr2tm2.3Dsn/Fgfr2+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS25: suture |
Present |
Regionally restricted |
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Expression was stronger in calvarial sutures compared to the wild-type.
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