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Gene Expression Data
Assay Details
Assay
Reference: J:231098 Theveniau-Ruissy M, et al., Coronary stem development in wild-type and Tbx1 null mouse hearts. Dev Dyn. 2016 Apr;245(4):445-59
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6389813
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-CD31
Detection system: Secondary antibody
Results
Specimen 2A lower left: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outflow tract distal part Present 2A lower left Expressed in periarterial plexus, contiguous with endothelial cells in the aortic sac region.
TS19: outflow tract endocardial cushion Present 2A lower left
TS19: ventricle endocardial lining Present 2A lower left
TS19: aortic sac Present Regionally restricted 2A lower left Expressed in the endothelium.
Specimen 2A lower middle: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: aortic sac Present 2A lower middle
TS19: outflow tract distal part Present 2A lower middle
TS19: outflow tract endocardial cushion Present 2A lower middle
TS19: ventricle endocardial lining Present 2A lower middle
Specimen 2A lower right: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outflow tract distal part Present 2A lower right
Specimen 2B lower left: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: coronary vascular plexus Present 2B lower left
TS20: outflow tract Present 2B lower left
TS20: heart ventricle Present Regionally restricted 2B lower left Expressed in ventricular plexus.
Specimen 2B lower middle: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: coronary vascular plexus Present 2B lower middle
TS20: outflow tract pulmonary component Present 2B lower middle
TS20: ascending aorta Present 2B lower middle Also expressed in the future coronary sinuses.
TS20: heart ventricle Present 2B lower middle Expressed in the incomplete progression of the ventricular plexus.
Specimen 2B lower right: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ascending aorta Present 2B lower right Also expressed in the future coronary sinuses.
TS20: coronary vascular plexus Present 2B lower right
TS20: outflow tract pulmonary component Present 2B lower right
TS20: heart ventricle Present 2B lower right Expressed in the incomplete progression of the ventricular plexus.
Specimen 4A left: embryonic day 12.5; Tbx1tm1Pa/Tbx1tm1Pa (more )
Structure Level Pattern Image Note
TS20: coronary vascular plexus Present 4A left Expressed at the expected site of the future right but not left coronary sinus. Incomplete progression of the ventricular coronary plexus was seen toward the periarterial plexus.
Specimen 4A middle left: embryonic day 12.5; Tbx1tm1Pa/Tbx1tm1Pa (more )
Structure Level Pattern Image Note
TS20: coronary vascular plexus Present 4A middle left Expressed at the expected site of the future right but not left coronary sinus. Incomplete progression of the ventricular coronary plexus was seen toward the periarterial plexus.
Specimen 4A middle right: embryonic day 12.5; Tbx1tm1Pa/Tbx1tm1Pa (more )
Structure Level Pattern Image Note
TS20: coronary vascular plexus Present 4A middle right Expressed at the expected site of the future right but not left coronary sinus. Incomplete progression of the ventricular coronary plexus was seen toward the periarterial plexus.
Specimen 4A right: embryonic day 12.5; Tbx1tm1Pa/Tbx1tm1Pa (more )
Structure Level Pattern Image Note
TS20: coronary vascular plexus Present 4A right Abnormal expansion of the ventricular plexus over the ventral region of the common arterial trunk was shown.
Specimen 7B upper: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: coronary vascular plexus Present 7B upper
Specimen 7B lower: embryonic day 12.5; Sema3ctm1.1Jra/Sema3ctm1.1Jra (more )
Structure Level Pattern Image Note
TS20: coronary vascular plexus Present 7B lower Same as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory