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Gene Expression Data
Assay Details
Assay
Reference: J:16551 Mansuy IM, et al., Variable and multiple expression of Protease Nexin-1 during mouse organogenesis and nervous system development. Development. 1993 Dec;119(4):1119-34
Assay type: RNA in situ
MGI Accession ID: MGI:6389008
Gene symbol: Serpine2
Gene name: serine (or cysteine) peptidase inhibitor, clade E, member 2
Probe: PN-1 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Probes were hydrolyzed prior to hybridization.
Results
Specimen 1 A/B: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: ectoplacental cone Strong 1A/B
TS28: decidua Strong 1A/B
TS11: embryo Present 1A/B
Specimen 1 C/D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: ectoplacental cone Present 1C/D
TS15: neural fold Present Regionally restricted 1C/D Expression is in the neuropepithelial cells of the closing neural tube.
Specimen 2 A/B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: diencephalon floor plate Present Regionally restricted 2A/B Expression is in subsets of ventricular progenitor cells.
TS17: hindbrain floor plate Present Regionally restricted 2A/B Expression is in subsets of ventricular progenitor cells.
TS17: midbrain floor plate Present Regionally restricted 2A/B Expression is in subsets of ventricular progenitor cells.
TS17: head Present Regionally restricted 2A/B Expression is in cartilage of the snout.
TS17: heart Present 2A/B
TS17: vertebral cartilage condensation Present 2A/B
TS17: liver Absent 2A/B
Specimen 2 C/D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain floor plate Present Regionally restricted 2C/D Expression is in subsets of neuroepithelial cells.
TS19: midbrain floor plate Present Regionally restricted 2C/D Expression is in subsets of neuroepithelial cells.
TS19: face Present Regionally restricted 2C/D Expression is in cartilage of the snout.
TS19: heart Present 2C/D
TS19: vertebral cartilage condensation Present 2C/D
TS19: liver Absent 2C/D
Specimen 2 E/F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: face Present Regionally restricted 2E/F Expression is in cartilage of the snout.
TS20: vertebral cartilage condensation Present 2E/F
TS20: liver Absent 2E/F
TS20: neocortex Absent 2E/F
Specimen 2 G/H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebellum Present 2G/H
TS21: dorsal root ganglion Present 2G/H
TS21: genital tubercle Present 2G/H
TS21: hindbrain floor plate Present 2G/H
TS21: lung Present 2G/H
TS21: midbrain floor plate Present 2G/H
TS21: rib cartilage condensation Present 2G/H
TS21: vertebral cartilage condensation Present 2G/H
TS21: skin Present Regionally restricted 2G/H
TS21: rhombic lip Present Regionally restricted 2G/H Expression is in cells in the rostral and caudal region.
TS21: liver Absent 2G/H
TS21: neocortex Absent 2G/H
Specimen 2 I/J: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cartilage condensation Present Regionally restricted 2I/J Expression is in the cartilage primordia of the snout.
TS22: basisphenoid cartilage condensation Present 2I/J
TS22: secondary palate Present 2I/J
TS22: rhombic lip Weak Regionally restricted 2I/J Expression is in cells in the rostral and caudal region.
TS22: liver Absent 2I/J
TS22: neocortex Absent 2I/J
Specimen 2 K/L: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: basioccipital bone Present 2K/L
TS24: cerebellum Present 2K/L
TS24: heart Present 2K/L
TS24: lung Present 2K/L
TS24: metanephros Present 2K/L
TS24: snout Present 2K/L
TS24: testis Present 2K/L
TS24: rib Present Regionally restricted 2K/L Expression is in the dorsal part of the ribs and is absent in the ossified ventral part.
TS24: liver Absent 2K/L
TS24: neocortex Absent 2K/L
Specimen 2 M/N: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: basal columns Present Regionally restricted 2O/P , 2M/N Expression is in neuroepithelial cells of the basal and intermediate plate lining the neural canal.
TS20: spinal cord mantle layer Present Regionally restricted 2O/P , 2M/N Expression is in neuroepithelial cells of the basal and intermediate plate lining the neural canal.
TS20: spinal cord floor plate Absent 2O/P , 2M/N
Specimen 4 A/B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: main olfactory bulb Present Regionally restricted 4A/B Expression is in the primitive external plexiform and glomerular zones.
TS21: olfactory epithelium Absent 4A/B
Specimen 4 C/D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: ethmoid bone Strong 4C/D
TS24: olfactory epithelium Strong 4C/D
TS24: main olfactory bulb Strong Regionally restricted 4C/D Expression is in the glomerular layer.
TS24: main olfactory bulb mitral cell layer Absent 4C/D
Specimen 4 E/F: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb glomerular layer Present 4E/F
TS27: main olfactory bulb mitral cell layer Absent 4E/F
Specimen 6 A/B: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: main olfactory bulb glomerular layer Present 6A/B
TS27: main olfactory bulb mitral cell layer Absent 6A/B
Specimen 6 C/D: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 6C/D
TS28: main olfactory bulb mitral cell layer Absent 6C/D
Specimen 6 E/F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 6E/F
TS28: main olfactory bulb mitral cell layer Absent 6E/F
Specimen 7A: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: brainstem Present 7A
TS27: cerebellum Present 7A
TS27: corpus striatum Present 7A
TS27: deep cerebellar nucleus Present 7A
TS27: inferior colliculus Present 7A
TS27: main olfactory bulb glomerular layer Present 7A
TS27: neocortex Present 7A
TS27: substantia nigra Present 7A
TS27: superior colliculus Present 7A
TS27: thalamus Present 7A
TS27: basal forebrain Present Regionally restricted 7A Expression is in the diagonal band of Broca.
TS27: cortical layer V Present Regionally restricted 7A Expression is in pyramidal neurons.
TS27: main olfactory bulb mitral cell layer Absent 7A
Specimen 7B: postnatal day 4 (more )
Structure Level Pattern Image Note
TS28: brainstem Present 7B
TS28: cerebellum Present 7B
TS28: corpus striatum Present 7B
TS28: deep cerebellar nucleus Present 7B
TS28: inferior colliculus Present 7B
TS28: main olfactory bulb glomerular layer Present 7B
TS28: neocortex Present 7B
TS28: substantia nigra Present 7B
TS28: superior colliculus Present 7B
TS28: thalamus Present 7B
TS28: basal forebrain Present Regionally restricted 7B Expression is in the diagonal band of Broca.
TS28: main olfactory bulb mitral cell layer Absent 7B
Specimen 7C: postnatal day 11 (more )
Structure Level Pattern Image Note
TS28: brainstem Present 7C
TS28: cerebellum Present 7C
TS28: corpus striatum Present 7C
TS28: deep cerebellar nucleus Present 7C
TS28: inferior colliculus Present 7C
TS28: main olfactory bulb glomerular layer Present 7C
TS28: neocortex Present 7C
TS28: substantia nigra Present 7C
TS28: superior colliculus Present 7C
TS28: thalamus Present 7C
TS28: basal forebrain Present Regionally restricted 7C Expression is in the diagonal band of Broca.
TS28: main olfactory bulb mitral cell layer Absent 7C
Specimen 7D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: brain Present Diffuse 7D Expression is throughout the brain.
TS28: main olfactory bulb glomerular layer Strong 7D
TS28: corpus striatum Strong Regionally restricted 7D
TS28: cortical layer V Strong Regionally restricted 7D Expression is in pyramidal nerons.
TS28: basal forebrain Strong Regionally restricted 7D Expression is in the diagonal band of Broca.
TS28: main olfactory bulb mitral cell layer Absent 7D
Specimen 9 Ca/b: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epithelium of seminal vesicle Present 9C a/b
Specimen not shown: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: cerebellum Present Regionally restricted Expression is in the cerebellar plate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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