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Gene Expression Data
Assay Details
Assay
Reference: J:166528 Zacharias AL, et al., Canonical Wnt/beta-catenin signaling is required for maintenance but not activation of Pitx2 expression in neural crest during eye development. Dev Dyn. 2010 Dec;239(12):3215-25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6388684
Gene symbol: Tfap2b
Gene name: transcription factor AP-2 beta
Antibody: anti-AP-2 beta/TFAP2B
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 6I: embryonic day 12.5; Ctnnb1tm2Kem/Ctnnb1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Littermate control; embryo was either fl/fl or fl/+.
Structure Level Pattern Image Note
TS20: eye mesenchyme Present Regionally restricted 6I Expression in neural crest of corneal, limbal and conjunctival mesenchyme.
TS20: eye epithelium Present Regionally restricted 6I Expression in surface ectoderm of presumptive conjunctiva and eyelid.
Specimen 6J: embryonic day 12.5; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: eye epithelium Present Regionally restricted 6J Expression patterns retained in mutant mice.
TS20: eye mesenchyme Present Regionally restricted 6J Expression patterns retained in mutant mice.
Specimen 6K: embryonic day 14.5; Ctnnb1tm2Kem/Ctnnb1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Littermate control; embryo was either fl/fl or fl/+.
Structure Level Pattern Image Note
TS22: eye mesenchyme Present Regionally restricted 6K Expression in neural crest of corneal, limbal and conjunctival mesenchyme.
TS22: conjunctiva epithelium Present Regionally restricted 6K Expression in surface ectoderm of presumptive conjunctiva and eyelid.
TS22: eyelid epithelium Present Regionally restricted 6K Expression in surface ectoderm of presumptive conjunctiva and eyelid.
Specimen 6L: embryonic day 14.5; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: conjunctiva epithelium Present Regionally restricted 6L Expression patterns retained in mutant mice.
TS22: eye mesenchyme Present Regionally restricted 6L Expression patterns retained in mutant mice.
TS22: eyelid epithelium Present Regionally restricted 6L Expression patterns retained in mutant mice.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory