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Gene Expression Data
Assay Details
Assay
Reference: J:272619 Aydogdu N, et al., TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827
Assay type: RNA in situ
MGI Accession ID: MGI:6385689
Gene symbol: Cxcl12
Gene name: C-X-C motif chemokine ligand 12
Probe: Cxcl12 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6E WT E13.5: embryonic day 13.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS21: ureteral mesenchyme Present Uniform 6E WT E13.5 Cxcl12
Specimen 6E Tbx2/3cDKO E13.5: embryonic day 13.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: ureteral mesenchyme subepithelial layer Present 6E Tbx2/3cDKO E13.5 Cxcl12 Expression was restricted to the inner layer of the ureteric mesenchyme.
Specimen 6E WT E14.5: embryonic day 14.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS22: ureteral mesenchyme outer layer Present 6E WT E14.5 Cxcl12
Specimen 6E Tbx2/3cDKO E14.5: embryonic day 14.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureteral mesenchyme subepithelial layer Present 6E Tbx2/3cDKO E14.5 Cxcl12 Expression was restricted to the inner layer of the ureteric mesenchyme.
Specimen 6E WT E18.5: embryonic day 18.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Structure Level Pattern Image Note
TS26: ureter Present Regionally restricted 6E WT E18.5 Cxcl12 Expression was restricted to the outer layer.
Specimen 6E Tbx2/3cDKO E18.5: embryonic day 18.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: ureter Present Regionally restricted 6E Tbx2/3cDKO E18.5 Cxcl12 Expression was restricted to the inner layer of the ureteric mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory