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Gene Expression Data
Assay Details
Assay
Reference: J:272619 Aydogdu N, et al., TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6385550
Gene symbol: Krt5
Gene name: keratin 5
Antibody: Anti-Keratin 5 (PRB-160P)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2D control: embryonic day 18.5; Tbx2tm2.2Vmc/?, Tbx3tm3.2Moon/?, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Double labeled: green - Krt5; red - Trp63 (assay MGI:6385551).
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present 2D control left Expression was detected in urothelial basal cells, which were also stained with Trp63.
Specimen 2D Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl: embryonic day 18.5; Tbx2tm2.2Vmc/Tbx2tm2.2Vmc, Tbx3tm3.2Moon/Tbx3tm3.2Moon, Tbx18tm4(cre)Akis/Tbx18+, Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: green - Krt5; red - Trp63 (assay MGI:6385551).
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present 2D Tbx18cre/+;Tbx2fl/fl;Tbx3fl/fl left Normal expression was detected in urothelial basal cells of the conditional mutant. The layer was also stained with Trp63.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory