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Gene Expression Data
Assay Details
Assay
Reference: J:93024 Grun F, et al., Aldehyde dehydrogenase 6, a cytosolic retinaldehyde dehydrogenase prominently expressed in sensory neuroepithelia during development. J Biol Chem. 2000 Dec 29;275(52):41210-8
Assay type: RNA in situ
MGI Accession ID: MGI:6384819
Gene symbol: Aldh1a3
Gene name: aldehyde dehydrogenase family 1, subfamily A3
Probe: Aldh6 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: retina Present Regionally restricted 7A Expression was detected in ventral and dorsal retina.
TS17: olfactory placode Present 7A
TS17: otocyst Present Regionally restricted 7A Expression was detected in the dorsal margin of the otic vesicle. Expression was transient and was not detected after E10.5.
TS17: olfactory epithelium Strong 7A

Specimen 7B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: optic vesicle Present Regionally restricted 7B Expression was detected in the dorsal and ventral margins of the optic vesicle.
TS15: head surface ectoderm Present Regionally restricted 7B Expression was detected in a large area of overlying surface head ectoderm.

Specimen 7C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: head surface ectoderm Weak 7C
TS17: neural retina Present Regionally restricted 7C Expression was more pronounced in the ventral neural retina.
TS17: olfactory epithelium Strong 7C

Specimen 7D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head surface ectoderm Present Regionally restricted 7D Expression was detected where the ectoderm invaginates at the dorsal and ventral margins of the optic cup.
TS19: neural retina Present Regionally restricted 7D Expression was more pronounced in the ventral neural retina. Staining was also transiently seen in the dorsal neural retina through E11.5.
TS19: olfactory epithelium Present Regionally restricted 7D Starting at E11.5, expression became progressively more restricted to the dorso-lateral neuroepithelium.

Specimen 7F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: neural retina Present Regionally restricted 7F Expression in neural retina is distinct in the ventral domain by E12.5.

Specimen 7G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: neural retina Weak 7G

Specimen 7H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: olfactory epithelium Present Punctate 7H
TS23: nasal mesenchyme Present Regionally restricted 7H A punctate expression was noted in the mesenchymal stroma directly underlying the sensory epithelium. Expression was restricted to discreet zones within the developing turbinates.

Specimen not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lateral ganglionic eminence Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory