Trp53 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:201153 Hamard PJ, et al., The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo. Genes Dev. 2013 Sep 1;27(17):1868-85
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6383912
Gene symbol:	Trp53
Gene name:	transformation related protein 53

Antibody:

anti-p53 (CM5, P53-PROTEIN-CM5)

Results

6C p53 +/+ (bottom) ©

Specimen 6C p53 +/+: postnatal day 10 (more

)

Structure	Level	Pattern	Image	Note
TS28: thymus	Present		6C p53 +/+ (bottom)

6C p53 deltaCTD/+ (bottom) ©

Specimen 6C p53 deltaCTD/+: postnatal day 10; Trp53^tm1.1Manf/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: thymus	Present		6C p53 deltaCTD/+ (bottom)

6C p53 deltaCTD/deltaCTD (bottom) ©

Specimen 6C p53 deltaCTD/deltaCTD: postnatal day 10; Trp53^tm1.1Manf/Trp53^tm1.1Manf (more

)

Structure	Level	Pattern	Image	Note
TS28: thymus	Present		6C p53 deltaCTD/deltaCTD (bottom)	Authors report no difference in basal expression levels.

8C p53 +/+ (bottom) ©

Specimen 8C p53 +/+: postnatal day 10 (more

)

Structure	Level	Pattern	Image	Note
TS28: liver	Present		8C p53 +/+ (bottom)

8C p53 deltaCTD/+ (bottom) ©

Specimen 8C p53 deltaCTD/+: postnatal day 10; Trp53^tm1.1Manf/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: liver	Present		8C p53 deltaCTD/+ (bottom)

8C p53 deltaCTD/deltaCTD (bottom) ©

Specimen 8C p53 deltaCTD/deltaCTD: postnatal day 10; Trp53^tm1.1Manf/Trp53^tm1.1Manf (more

)

Structure	Level	Pattern	Image	Note
TS28: liver	Present		8C p53 deltaCTD/deltaCTD (bottom)	Authors report no difference in basal expression levels.

9C p53 +/+ (bottom) ©

Specimen 9C p53 +/+: postnatal day 10 (more

)

Structure	Level	Pattern	Image	Note
TS28: spleen	Present		9C p53 +/+ (bottom)

9C p53 deltaCTD/+ (bottom) ©

Specimen 9C p53 deltaCTD/+: postnatal day 10; Trp53^tm1.1Manf/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: spleen	Strong		9C p53 deltaCTD/+ (bottom)	Authors report a significant and dose-dependent increase in expression.

Specimen 9C p53 deltaCTD/deltaCTD: postnatal day 10; Trp53^tm1.1Manf/Trp53^tm1.1Manf (more

)

Structure	Level	Pattern	Image	Note
TS28: spleen	Very strong		9C p53 deltaCTD/deltaCTD (bottom)	Authors report a significant and dose-dependent increase in expression.

Specimen S5A p53 +/+: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: liver	Present		S5A p53 +/+ (bottom)

Specimen S5A p53 deltaCTD/+: embryonic day 18.5; Trp53^tm1.1Manf/Trp53⁺ (more

)

Structure	Level	Pattern	Image	Note
TS26: liver	Strong		S5A p53 deltaCTD/+ (bottom)	Authors report a significant and dose-dependent increase in expression.

Specimen S5A p53 deltaCTD/deltaCTD: embryonic day 18.5; Trp53^tm1.1Manf/Trp53^tm1.1Manf (more

)

Structure	Level	Pattern	Image	Note
TS26: liver	Very strong		S5A p53 deltaCTD/deltaCTD (bottom)	Authors report a significant and dose-dependent increase in expression.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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