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Gene Expression Data
Assay Details
Assay
Reference: J:245959 Ho UY, et al., Patched1 patterns Fibroblast growth factor 10 and Forkhead box F1 expression during pulmonary branch formation. Mech Dev. 2017 Oct;147:37-48
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6379787
Gene symbol: Ptch1
Gene name: patched 1
Reporter: lacZ
Direct Detection
Results
Specimen 1I: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS19: lung mesenchyme Present Regionally restricted 1I Expression was detected in the subepithelial mesenchyme of lung.
Specimen 1J: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: lung mesenchyme Present Widespread 1J In the conditional mutant, expression was expanded throughout the mesenchyme beyond the normal subepithelial region.
Specimen 1K: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS19: esophagus Absent 1K
TS19: trachea Absent 1K
Specimen 1L: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: esophagus mesenchyme Present 1L
TS19: trachea mesenchyme Present 1L
Specimen 1M: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps (more )
Structure Level Pattern Image Note
TS19: lobar bronchus mesenchyme Present Regionally restricted 1M Expression was detected in the subepithelial mesenchyme surrounding the bronchi in the distal airways.
Specimen 1N: embryonic day 11.5; Ptch1tm1Bjw/Ptch1tm1Mps, Twist2tm1(cre)Dor/Twist2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: lobar bronchus mesenchyme Present Widespread 1N Expression was throughout the distal mesenchyme in the conditional mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory