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Gene Expression Data
Assay Details
Assay
Reference: J:51693 Grimm C, et al., Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern. Dev Genet. 1998;23(4):299-316
Assay type: RNA in situ
MGI Accession ID: MGI:6364193
Gene symbol: Pax6
Gene name: paired box 6
Probe: Pax6 probe
Probe preparation: Antisense RNA
Results
Specimen 5A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lens vesicle anterior epithelium Present 5A
TS20: neural retina Present 5A
TS20: cornea epithelium Present 5A surface ectoderm
TS20: lens vesicle Present Regionally restricted 5A Expressed in the elongating primary lens fiber cells.
Specimen 5B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: lens anterior epithelium Present 5B
TS21: neural retina Present 5B
TS21: lens epithelium Present Regionally restricted 5B Expressed in the anterior epithelium and the bow region.
TS21: cornea epithelium Weak 5B
TS21: lens fiber Weak 5B
Specimen 5C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: neural retina Present 5C
TS23: lens anterior epithelium Present 5C Including the equator region.
TS23: cornea epithelium Absent 5C
Specimen 5D: embryonic day 12.5; Pitx3ak/Pitx3ak (more )
Structure Level Pattern Image Note
TS20: neural retina Present 5D
TS20: cornea epithelium Present 5D surface ectoderm
TS20: lens vesicle epithelium Present 5D
TS20: lens vesicle Present Regionally restricted 5D Expressed in the epithelium and the disorganized cells in the rudimentary lens vesicle.
Specimen 5E/G: embryonic day 13.5; Pitx3ak/Pitx3ak (more )
Structure Level Pattern Image Note
TS21: lens Present Widespread 5E , 5G Expressed throughout the lens remnant and in the persisting lens stalk.
TS21: cornea epithelium Present 5E
TS21: neural retina Present 5E
Specimen 5F: embryonic day 15.5; Pitx3ak/Pitx3ak (more )
Structure Level Pattern Image Note
TS23: neural retina Present 5F
TS23: cornea epithelium Weak 5F
TS23: lens Present 5F Still expressed in the structures, which might be considered as a remnant lens vesicle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory