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Gene Expression Data
Assay Details
Assay
Reference: J:119274 Georgia S, et al., p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors. Dev Biol. 2006 Oct 1;298(1):22-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6364178
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase3
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 3A: embryonic day 10.5 (more )
Note: Double labeled: green - Casp3; red - Isl1 (assay MGI:6364177).
Structure Level Pattern Image Note
TS17: pancreas primordium Trace Regionally restricted 3A Expression rarely observed in pancreatic epithelium.
Specimen 3B: embryonic day 10.5; Cdkn1ctm1Sje/Cdkn1c+, Hes1tm1Fgu/Hes1tm1Fgu (more )
Note: Double labeled: green - Casp3; red - Isl1 (assay MGI:6364177).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Widespread 3B
Specimen 6A: embryonic day 11.5 (more )
Note: Double labeled: green - Casp3; red - Glucagon (Gcg; assay MGI:6364174).
Structure Level Pattern Image Note
TS19: pancreas primordium Ambiguous 6A Apoptotic pancreatic progenitors rarely obeserved within pancreatic buds.
Specimen 6B: embryonic day 11.5; Hes1tm1Fgu/Hes1tm1Fgu (more )
Note: Double labeled: green - Casp3; red - Glucagon (Gcg; assay MGI:6364174).
Structure Level Pattern Image Note
TS19: pancreas primordium Ambiguous 6B Apoptotic pancreatic progenitors rarely obeserved within pancreatic buds.
Specimen 6C/E: embryonic day 11.5; Cdkn1ctm1Sje/Cdkn1ctm1Sje (more )
Note: Triple labeled: green - Casp3; red - Glucagon (Gcg; assay MGI:6364174); blue - DAPI.
Structure Level Pattern Image Note
TS19: pancreas primordium epithelium Present Widespread 6C , 6E
Specimen 6D/F: embryonic day 11.5; Cdkn1ctm1Sje/Cdkn1c+, Hes1tm1Fgu/Hes1tm1Fgu (more )
Note: Triple labeled: green - Casp3; red - Glucagon (Gcg; assay MGI:6364174); blue - DAPI.
Structure Level Pattern Image Note
TS19: pancreas primordium epithelium Absent 6D , 6F Little or no evidence of apoptotic cells in pancreatic epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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