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Gene Expression Data
Assay Details
Assay
Reference: J:119144 Seo S, et al., The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development. Dev Biol. 2006 Jun 15;294(2):458-70
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6364008
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-CD31
Results
Specimen 1A: embryonic day 8.25 (more )
Structure Level Pattern Image Note
TS12: cardinal vein Present 1A
TS12: dorsal aorta Present 1A
Specimen 1B: embryonic day 8.25; Foxc1tm1Blh/Foxc1tm1Blh, Foxc2tm1Blh/Foxc2tm1Blh (more )
Structure Level Pattern Image Note
TS12: cardinal vein Present 1B
TS12: dorsal aorta Present 1B
Specimen 1C: embryonic day 8.25; Foxc1tm1Blh/Foxc1tm1Blh, Foxc2tm1Blh/Foxc2tm1Blh (more )
Structure Level Pattern Image Note
TS12: cardinal vein Present Regionally restricted 1C Authors report arteriovenous malformation (AVM) in compound homozygote caused by fusion of blood vessels.
TS12: dorsal aorta Present Regionally restricted 1C Authors report arteriovenous malformation (AVM) in compound homozygote caused by fusion of blood vessels.
Specimen 2S: embryonic day 9.0 (more )
Note: Double labeled: red - Pecam1; green - COUP-TFII (Nr2f2 assay MGI:6364009).
Structure Level Pattern Image Note
TS14: artery Present 2S
TS14: vein Present 2S
Specimen 2T: embryonic day 9.0; Foxc1tm1Blh/Foxc1tm1Blh, Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: Double labeled: red - Pecam1; green - COUP-TFII (Nr2f2 assay MGI:6364009).
Structure Level Pattern Image Note
TS14: vascular element Present 2T
Specimen 2U: embryonic day 9.0 (more )
Note: Double labeled: red - Pecam1; green - Ephb4 (assay MGI:6364010).
Structure Level Pattern Image Note
TS14: artery Present 2U
TS14: vein Present 2U
Specimen 2V: embryonic day 9.0; Foxc1tm1Blh/Foxc1tm1Blh, Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: Double labeled: red - Pecam1; green - Ephb4 (assay MGI:6364010).
Structure Level Pattern Image Note
TS14: vascular element Present 2V
Specimen 2W: embryonic day 9.0 (more )
Note: Double labeled: red - Pecam1; green - Lyve1 (assay MGI:6364011).
Structure Level Pattern Image Note
TS14: cardinal vein Present 2W
Specimen 2X: embryonic day 9.0; Foxc1tm1Blh/Foxc1tm1Blh, Foxc2tm1Blh/Foxc2tm1Blh (more )
Note: Double labeled: red - Pecam1; green - Lyve1 (assay MGI:6364011).
Structure Level Pattern Image Note
TS14: cardinal vein Present 2X
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory