Gene Expression Data
Assay Details
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Assay
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Reference:
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J:273625
Takahashi M, et al., An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6361654
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Gene symbol:
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Timp2
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Gene name:
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tissue inhibitor of metalloproteinase 2
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Probe:
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Timp2 cDNA4
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Probe preparation:
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Antisense labelled with S35 RNA
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Visualized with:
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Autoradiography
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Results
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Specimen
2e:
embryonic day 14.5
(more  )
Specimen
2e:
(close  )
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Genetic Background:
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ICR
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: mandible ramus |
Present |
Regionally restricted |
2e
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Expression is in the condylar anlage and periosteum.
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| TS22: periosteum |
Present |
Regionally restricted |
2e
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Expression is in the condylar anlage and periosteum.
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Specimen
2j:
embryonic day 15.5
(more )
Specimen
2j:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 15.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: mandible ramus |
Present |
Regionally restricted |
2j
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Expression is in the periosteum, perichondrium, and is weak in a region posterior to the newly formed condylar cartilage consisting of a mesenchymal cell condensation.
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| TS23: perichondrium |
Present |
Regionally restricted |
2j
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Expression is in the periosteum/perichondrium of the condylar anlage.
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| TS23: periosteum |
Present |
Regionally restricted |
2j
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Expression is in the periosteum/perichondrium of the condylar anlage.
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Specimen
3e:
embryonic day 16.5
(more )
Specimen
3e:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: mandible condylar process |
Present |
Regionally restricted |
3e
,
3e'
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Expression is in the fibrous cell zone and polymorphic cell zone and in the perichondrium and periosteum, and is weak in the flattened cell zone.
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| TS24: perichondrium |
Present |
Regionally restricted |
3e'
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3e
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Expression is in the perichondrium and periosteum of the condylar anlage.
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| TS24: periosteum |
Present |
Regionally restricted |
3e'
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3e
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Expression is in the perichondrium and periosteum of the condylar anlage.
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Specimen
3k:
embryonic day 18.5
(more )
Specimen
3k:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 18.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: mandible condylar process |
Present |
Regionally restricted |
3k'
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3k
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Expression is in the fibrous cell zone, polymorphic cell zone, perichondrium, periosteum, articular disc, and is weak in the flattened cell zone. Expression is in the anlagen of the articular disc.
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| TS26: perichondrium |
Present |
Regionally restricted |
3k'
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3k
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Expression is in the perichondrium and periosteum of the condylar anlage.
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| TS26: periosteum |
Present |
Regionally restricted |
3k'
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3k
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Expression is in the perichondrium and periosteum of the condylar anlage.
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Specimen
4e:
embryonic day 12.5
(more )
Specimen
4e:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 12.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4j:
embryonic day 13.5
(more )
Specimen
4j:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 13.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: perichondrium |
Present |
Regionally restricted |
4j
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Expression is in the perichondrium and chondrocytes at the epiphyseal end of the tibia.
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| TS21: tibia-fibula pre-cartilage condensation |
Present |
Regionally restricted |
4j
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Expression is in the perichondrium and chondrocytes at the epiphyseal end of the tibia.
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Specimen
4o:
embryonic day 14.5
(more )
Specimen
4o:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: perichondrium |
Present |
Regionally restricted |
4o
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Expression is continuous from the perichondrium to the periosteum and in chondrocytes at the epiphyseal end of the tibia.
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| TS22: periosteum |
Present |
Regionally restricted |
4o
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Expression is continuous from the perichondrium to the periosteum and in chondrocytes at the epiphyseal end of the tibia.
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| TS22: tibia cartilage condensation |
Present |
Regionally restricted |
4o
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Expression is continuous from the perichondrium to the periosteum and in chondrocytes at the epiphyseal end of the tibia.
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Specimen
5e:
embryonic day 16.5
(more )
Specimen
5e:
(close )
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Genetic Background:
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ICR
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Age:
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embryonic day 16.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: perichondrium |
Present |
Regionally restricted |
5e
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Expression is in the perichondrium and the bone collar of the developing sphenoid bone cartilage.
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| TS24: sphenoid bone |
Present |
Regionally restricted |
5e
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Expression is in the perichondrium and the bone collar of the developing sphenoid bone cartilage.
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| TS24: trigeminal ganglion |
Present |
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5e
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Analysis Tools