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Gene Expression Data
Assay Details
Assay
Reference: J:273053 Shih HP, et al., A Gene Regulatory Network Cooperatively Controlled by Pdx1 and Sox9 Governs Lineage Allocation of Foregut Progenitor Cells. Cell Rep. 2015 Oct 13;13(2):326-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6361464
Gene symbol: Nkx6-1
Gene name: NK6 homeobox 1
Antibody: Anti-Nkx6.1
Detection system: Secondary antibody coupled to Cy5
Results
Specimen S1JJ: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1JJ
Specimen S1KK: embryonic day 10.5; Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1KK
Specimen S1LL: embryonic day 10.5; Pdx1tm2Cvw/Pdx1+ (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1LL
Specimen S1MM: embryonic day 10.5; Pdx1tm2Cvw/Pdx1+, Sox9tm1Gsr/Sox9+, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1MM
Specimen S1NN: embryonic day 10.5; Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: pancreas primordium Present S1NN
Specimen S1OO: embryonic day 10.5; Pdx1tm2Cvw/Pdx1tm2Cvw (more )
Structure Level Pattern Image Note
TS17: pancreas primordium Absent S1OO
Specimen S1PP: embryonic day 10.5; Pdx1tm2Cvw/Pdx1tm2Cvw, Sox9tm1Gsr/Sox9tm1Gsr, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: foregut Weak S1PP Expression was reduced in the Pdx1;Sox9 mutant embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory