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Gene Expression Data
Assay Details
Assay
Reference: J:99697 Liu W, et al., Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol. 2005 Jul 15;283(2):282-93
Assay type: RNA in situ
MGI Accession ID: MGI:6355427
Gene symbol: Dlx2
Gene name: distal-less homeobox 2
Probe: Dlx2 probe20
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present 4G
Specimen 4H: embryonic day 10.5; Bmp4tm1Jfm/Bmp4tm1.1Jfm, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Absent 4H Ectoderm expression was lost.
TS17: 1st branchial arch mandibular component mesenchyme Present Regionally restricted 4H Expression extended into distal mesenchyme of mutant embryos.
Specimen 4I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present 4I
Specimen 4J: embryonic day 10.5; Bmp4tm1Jfm/Bmp4tm1.1Jfm, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Absent 4J No expression in mandibular epithelium.
TS17: 1st branchial arch mandibular component mesenchyme Present Regionally restricted 4J Expression expanded into mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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