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Gene Expression Data
Assay Details
Assay
Reference: J:99697 Liu W, et al., Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol. 2005 Jul 15;283(2):282-93
Assay type: RNA in situ
MGI Accession ID: MGI:6355425
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Probe: Isl2 probe26
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4A: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component ectoderm Present 4A
Specimen 4B: embryonic day 9.5; Bmp4tm1Jfm/Bmp4tm1.1Jfm, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component ectoderm Weak 4B Reduced expression in mutant mandible at E9.5.
Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present 4C
Specimen 4D: embryonic day 10.5; Bmp4tm1Jfm/Bmp4tm1.1Jfm, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Absent 4D Expression absent in mutant mandible at E10.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory