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Gene Expression Data
Assay Details
Assay
Reference: J:99697 Liu W, et al., Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol. 2005 Jul 15;283(2):282-93
Assay type: RNA in situ
MGI Accession ID: MGI:6355423
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe91
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3C: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: 1st branchial arch mandibular component ectoderm Present Regionally restricted 3C Expression in proximal mandibular ectoderm
Specimen 3D: embryonic day 9.0; Bmp4tm1Jfm/Bmp4tm1.1Jfm, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS14: 1st branchial arch mandibular component ectoderm Present Regionally restricted 3D Expression unchanged in mutant compared to wild type.
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present Regionally restricted 6A Expression in proximal mandibular ectoderm
Specimen 6B: embryonic day 10.5; Bmp4tm1Jfm/Bmp4tm1.1Jfm, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present Regionally restricted 6B No expression in proximal ectoderm. Expression only in distal ectoderm of mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory