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Gene Expression Data
Assay Details
Assay
Reference: J:99697 Liu W, et al., Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol. 2005 Jul 15;283(2):282-93
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6355408
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 9.5; Bmp4tm2Blh/Bmp4+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Present Regionally restricted 1A Expression in distal aspect of mandibular process ectoderm.
Specimen 1B: embryonic day 9.5; Bmp4tm2Blh/Bmp4+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component ectoderm Present Regionally restricted 1B Expression in distal aspect of mandibular process ectoderm.
Specimen E10.5 not shown: embryonic day 10.5; Bmp4tm2Blh/Bmp4+ (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present Regionally restricted Expression in distal aspect of mandibular process ectoderm.
Specimen 3A: embryonic day 9.5; Bmp4tm2Blh/Bmp4+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component ectoderm Present Regionally restricted 3A Expression in distal mandibular ectoderm.
Specimen 3B: embryonic day 9.5; Bmp4tm1Jfm/Bmp4tm2Blh, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component ectoderm Present Regionally restricted 3B Expression in distal mandibular ectoderm.
Specimen 3I: embryonic day 10.5; Bmp4tm2Blh/Bmp4+ (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Present Regionally restricted 3I Expression in oral ectoderm.
Specimen 3J: embryonic day 10.5; Bmp4tm1Jfm/Bmp4tm2Blh, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Weak Regionally restricted 3J Reduced expressionein oral ectoderm.
Specimen 5I: embryonic day 12.5; Bmp4tm2Blh/Bmp4+ (more )
Structure Level Pattern Image Note
TS20: mandible primordium Present Widespread 5I Broad expression in mandibular mesenchyme.
Specimen 5J: embryonic day 12.5; Bmp4tm1Jfm/Bmp4tm2Blh, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: mandible primordium Weak Regionally restricted 5J Authors report residual expression in only a small group of cells in the distal mandible.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory