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Gene Expression Data
Assay Details
Assay
Reference: J:74063 Joronen K, et al., Temporospatial expression of tissue inhibitors of matrix metalloproteinases-1, -2 and -3 during development, growth and aging of the mouse skeleton. Histochem Cell Biol. 2000 Aug;114(2):157-65
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6323430
Gene symbol: Timp2
Gene name: tissue inhibitor of metalloproteinase 2
Antibody: anti-TIMP-2
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to alkaline phosphatase
Results
Specimen 6A: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: synovium Present 6A
TS28: trabecular bone Present Regionally restricted 6A Expressed in the lining cells.
Specimen 6B: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: trabecular bone Present Regionally restricted 6B Expressed in the lining cells.
TS28: long bone epiphysis Weak Regionally restricted 6B Expressed in the hypertrophic condrocytes.
Specimen 6C: postnatal day 20 (more )
Structure Level Pattern Image Note
TS28: synovium Present 6C
Specimen 6D: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: femur epiphysis Present 6D Expressed in the chondrocytes both intracellularly and pericellularly and in the lining cells.
TS28: tibia epiphysis Present 6D Expressed in the chondrocytes both intracellularly and pericellularly and in the lining cells.
TS28: synovium Present 6D
TS28: articular cartilage Present Regionally restricted 6D Expressed in the superficial and the deep zones.
Specimen 6E: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: long bone epiphysis Present 6E Expressed in the chondrocytes both intracellularly and pericellularly.
Specimen 6F: postnatal month 4 (more )
Structure Level Pattern Image Note
TS28: synovium Present 6F
TS28: articular cartilage Present Regionally restricted 6F Expressed in the superficial and the deep zones.
Specimen 6G: postnatal month 15 (more )
Structure Level Pattern Image Note
TS28: synovium Present 6G Strongest expression.
TS28: articular cartilage Present 6G Expressed in the chondrocytes both intracellularly and pericellularly.
TS28: femur epiphysis Present 6G Expressed in the chondrocytes both intracellularly and pericellularly.
TS28: tibia epiphysis Present 6G Expressed in the chondrocytes both intracellularly and pericellularly.
Specimen 6H: postnatal month 15 (more )
Structure Level Pattern Image Note
TS28: articular cartilage Present 6H Expressed in the chondrocytes both intracellularly and pericellularly.
TS28: femur epiphysis Present 6H Expressed in the chondrocytes both intracellularly and pericellularly.
TS28: tibia epiphysis Present 6H Expressed in the chondrocytes both intracellularly and pericellularly.
Specimen 6I: postnatal month 15 (more )
Structure Level Pattern Image Note
TS28: synovium Present 6I Strongest expression.
Specimen not shown: postnatal month 9 (more )
Structure Level Pattern Image Note
TS28: articular cartilage Present Expressed in the chondrocytes both intracellularly and pericellularly.
TS28: femur epiphysis Present Expressed in the chondrocytes both intracellularly and pericellularly.
TS28: tibia epiphysis Present Expressed in the chondrocytes both intracellularly and pericellularly.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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