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Gene Expression Data
Assay Details
Assay
Reference: J:271100 Shen B, et al., Genetic dissection of tie pathway in mouse lymphatic maturation and valve development. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1221-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6314705
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Results
Specimen 1D ICD/ICD PECAM-1: embryonic day 10.5; Tie1tm1.1Yuhe/Tie1tm1.1Yuhe, Tg(EIIa-cre)C5379Lmgd/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Tie1 (assay MGI:6314704).
Structure Level Pattern Image Note
TS17: blood vessel endothelium Present 1D ICD/ICD PECAM-1 , 1D ICD/ICD Overlay Authors report blood vessels formed normally in homozygous mutant mice.

Specimen 1D +/ICD PECAM-1: embryonic day 10.5; Tie1tm1.1Yuhe/Tie1+, Tg(EIIa-cre)C5379Lmgd/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Tie1 (assay MGI:6314704).
Structure Level Pattern Image Note
TS17: blood vessel endothelium Present 1D +/ICD Overlay , 1D +/ICD PECAM-1

Specimen 1D +/+ PECAM-1: embryonic day 10.5 (more )
Note: Double labeled: green - Pecam1; red - Tie1 (assay MGI:6314704).
Structure Level Pattern Image Note
TS17: blood vessel endothelium Present 1D +/+ PECAM-1 , 1D +/+ Overlay

Specimen 1E ICD/ICD PECAM-1: embryonic day 13.5; Tie1tm1.1Yuhe/Tie1tm1.1Yuhe, Tg(EIIa-cre)C5379Lmgd/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:6314706).
Structure Level Pattern Image Note
TS21: artery Present 1E ICD/ICD PECAM-1 , 1E ICD/ICD Overlay Authors report artery and vein formed normally in homozygous mutant compared to control mice.
TS21: vein Present 1E ICD/ICD PECAM-1 , 1E ICD/ICD Overlay Authors report artery and vein formed normally in homozygous mutant compared to control mice.

Specimen 1E +/ICD PECAM-1: embryonic day 13.5; Tie1tm1.1Yuhe/Tie1+, Tg(EIIa-cre)C5379Lmgd/0 (more )
Note: Conditional mutant. Double labeled: green - Pecam1; red - Lyve1 (assay MGI:6314706).
Structure Level Pattern Image Note
TS21: artery Present 1E +/ICD PECAM-1 , 1E +/ICD Overlay
TS21: vein Present 1E +/ICD PECAM-1 , 1E +/ICD Overlay

Specimen 1E +/+ PECAM-1: embryonic day 13.5 (more )
Note: Double labeled: green - Pecam1; red - Lyve1 (assay MGI:6314706).
Structure Level Pattern Image Note
TS21: artery Present 1E +/+ PECAM-1 , 1E +/+ Overlay
TS21: vein Present 1E +/+ PECAM-1 , 1E +/+ Overlay

Specimen 3B PECAM-1: postnatal week 5 (more )
Note: Double labeled: green - Pecam1; red - Tie1 (assay MGI:6314704).
Structure Level Pattern Image Note
TS28: ear skin Present 3B Overlay , 3B PECAM-1


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory