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Gene Expression Data
Assay Details
Assay
Reference: J:149237 Perez-Balaguer A, et al., Shh dependent and independent maintenance of basal midbrain. Mech Dev. 2009 May-Jun;126(5-6):301-13
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6304465
Gene symbol: Pou4f1
Gene name: POU domain, class 4, transcription factor 1
Results
Specimen 7A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain mantle layer Present Regionally restricted 7A Expression was detected in the red nucleus.

Specimen 7B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: midbrain tegmentum Present Regionally restricted 7B Expression was detected in the red nucleus.

Specimen 7D: embryonic day 12.5; Shhtm2Amc/Shhtm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: midbrain mantle layer Present Regionally restricted 7D Expression was maintained in the red nucleus of the conditional mutant.
TS20: midbrain Present Regionally restricted 7D Ectopic immunopositive cells took up a ventral position, crossing the midline.

Specimen 7E: embryonic day 18.5; Shhtm2Amc/Shhtm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: midbrain tegmentum Present Regionally restricted 7E Red nucleus expression appeared slightly diffused and the usual compacted shape was less obvious.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory